Description
Indication & Scope
Deanxit® Flupentixol and Melitracen Tablets provides management of mild‑to‑moderate depression and anxiety. It is also applied for neurasthenia, psychogenic depression, depressive neurosis, masked depression, psychosomatic disorders accompanied by anxiety and apathy, menopausal depression, dysphoria and depressive mood among alcohol‑dependent or drug‑addicted individuals.
- Mechanism: This fixed‑dose combination exerts synergistic central nervous system regulation. Low‑dose flupentixol blocks presynaptic dopamine autoreceptors, raising dopamine transmission to deliver anxiolytic and mood‑lifting effects. Melitracen, a tricyclic agent, inhibits neuronal re‑uptake of serotonin and norepinephrine within synaptic clefts, improving depressed mood.
- Drug class: Combined psychotropic preparation consisting of a thioxanthene neuroleptic and a tricyclic antidepressant; prescription‑only psychotherapeutic medicine.
- Clinical use: Clinically prescribed for short‑term symptomatic control of mild‑moderate anxiety and depressive episodes, as well as mood disturbances secondary to somatic or psychosomatic diseases. It is frequently used to relieve emotional discomfort accompanied by functional somatic complaints under physician supervision.
| Generic Name | Flupentixol and Melitracen Tablets |
| Brand Name | Deanxit® |
| Ingredient | Flupentixol and Melitracen |
| Dosage Form | Tablets |
| Package | (Flupentixol 0.5mg + Melitracen 10mg) *20 tablets/box |
| Conditions Treated | Mild‑to‑moderate depression, mild‑to‑moderate anxiety, neurasthenia, masked depression, menopausal depressive mood, emotional agitation and depression in people with alcohol or drug dependence, psychosomatic illnesses with anxiety and emotional apathy |
| Taboos | Hypersensitivity to flupentixol, melitracen or any excipient. Early recovery phase following myocardial infarction, bundle‑branch conduction block, untreated narrow‑angle glaucoma, acute intoxication from alcohol, barbiturates or opiates |
| Place of origin | Ottiliavej 9, DK-2500, Valby, Denmark |
| Prescription type | Prescription‑only |
| Storage Conditions | Seal and store below 25 °C, kept away from strong light and excessive heat |
| Manufacturer | H. Lundbeck A/S |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20171104 |
| Approval Date | Feb 22, 2022 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: For average adults: initial routine dose is 2 tablets per day, one tablet in the morning and one at noon. For severe symptoms, morning dose may be increased to 2 tablets; the maximum daily dose shall not exceed 4 tablets. For elderly patients above 65 years: 1 tablet taken in the morning is generally sufficient. Maintenance dose after symptom relief is usually 1 tablet once every morning.
Time: Doses should be administered in the morning and at noon; evening or late‑afternoon intake should be avoided to lower insomnia risk. Long‑term dosage adjustment and treatment duration require regular professional medical assessment.
Instructions for use: For oral swallowing with water only, do not chew or crush tablets. Treatment cannot be stopped abruptly; gradual dose tapering is advised under medical guidance to reduce withdrawal‑related discomfort.
Interaction: This medicine may reduce the hypotensive effect of adrenergic‑neuron‑blocking antihypertensive agents such as guanethidine. Flupentixol may antagonize the therapeutic effects of levodopa and other dopaminergic drugs. Combined use with monoamine‑oxidase inhibitors carries the risk of hypertensive crisis and is strictly forbidden within the two‑week wash‑out period.
Side effects: Mild and infrequent adverse events at standard doses. Occasional dry mouth, constipation, dizziness, fatigue, or sleep disturbance may appear in the early treatment phase. Rarely, extrapyramidal reactions, tachycardia, allergic skin rash may occur.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What kinds of mood‑related symptoms is Flupentixol and Melitracen Tablets indicated to manage?
Deanxit is indicated for mild‑to‑moderate depression and anxiety, as well as mood disturbances such as neurasthenia, masked depression and menopausal depressive mood.
Why should late‑day or evening administration of Flupentixol and Melitracen Tablets be avoided?
Late‑day or evening administration increases the risk of insomnia because of the drug’s potential stimulant‑like effect on mental alertness.
What hard‑limit maximum daily quantity of Flupentixol and Melitracen Tablets is allowed for adult use?
The maximum daily dose for adults must not exceed four tablets under any circumstance.
What critical time‑interval restriction exists for switching from monoamine‑oxidase inhibitors to Flupentixol and Melitracen Tablets?
A minimum two‑week wash‑out period after stopping monoamine‑oxidase inhibitors is required before starting Deanxit to prevent dangerous hypertensive reactions.
Deanxit® | Flupentixol and Melitracen Tablets | Mild to Moderate Depression and Anxiety | DengYueRX
INN: Flupentixol and Melitracen Tablets
Indications: Mild to moderate depression and anxiety
Dosage Form: Flupentixol and Melitracen Tablets
Strength: (Flupentixol 0.5mg + Melitracen 10mg) /tablet
Original price was: $13.10.$11.13Current price is: $11.13.
