Description

Indication & Scope

Finerenone treats adults with type 2 diabetes and chronic kidney disease to lower risks of kidney function deterioration, end-stage renal disease and cardiovascular events, used alongside standard blood sugar and blood pressure control.

Mechanism
A nonsteroidal selective mineralocorticoid receptor antagonist that inhibits receptor overactivation, eases fibrosis and inflammation, and protects kidneys and heart.
Drug class
Nonsteroidal MRA, oral film-coated nephrocardioprotective tablet.
Clinical use
Phase III trials prove its reliable safety and renal-cardiovascular benefits. Taken once daily; start at 10 mg, adjust to 20 mg based on potassium and renal tolerance. It is the first approved nonsteroidal MRA for diabetic kidney disease.

Specification

Generic Name	Finerenone Tablets
Brand Name	Kerendia®
Ingredient	Finerenone
Dosage Form	Film-coated tablet
Package	10mg/tablet; 20mg/tablet
Conditions Treated	Treated Reduce risks of renal function decline, end-stage kidney disease, cardiovascular death, myocardial infarction and heart failure hospitalization in adult patients with type 2 diabetes mellitus complicated with chronic kidney disease, used as adjunctive therapy under standard glucose and blood pressure management
Taboos	Contraindicated in patients with hypersensitivity to finerenone or any excipients, patients with severe hyperkalemia, patients with acute kidney injury
Place of origin	Germany
Priscription Type	Prescription drug (Rx)
Storage Conditions	Store below 30℃, sealed and away from moisture
Manufacturer	Bayer AG
Registration Authority	National Medical Products Administration (NMPA)
Approval number	JX20210039
Date of Revision	May 12, 2023
Shelf Life	36 months

How to use ?

Recommended Dose: Start 10 mg oral once daily, increase to 20 mg once daily based on serum potassium and renal function, taken with or without food.

Time: Long-term daily continuous administration, regular monitoring of kidney function and blood potassium required.

Interaction: Avoid strong CYP3A4 inhibitors; closely check potassium with potassium-sparing diuretics or potassium supplements, can be combined with routine hypoglycemic and antihypertensive drugs.

Side effects: Common mild reactions include hyperkalemia, hypotension, hyponatremia and fatigue; severe adverse events are rare.

Important Notice

This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What are the benefits of finerenone?

Finerenone slows CKD progression and cuts cardiovascular risks

What is the use of finerenone tablet?

Avoid grapefruit and grapefruit juice during Kerendia treatment, as they dangerously elevate its blood concentration. Alcohol’s impact remains unclear.

When to stop finerenone?

Clinicians advise stopping finerenone for intolerable adverse reactions, including unmanageable hyperkalemia and hypotension.

Does finerenone reduce creatinine?

Studies show finerenone markedly lowers UACR (≥30% in most patients), driving its renal and cardiovascular benefits.