Description

Indication & Scope

DIFLUCAN® is a prescription triazole antifungal indicated for the treatment and prevention of Candida infections, including oropharyngeal and esophageal candidiasis, vulvovaginal candidiasis, disseminated candidiasis, and Candida infections in immunocompromised patients. It is also indicated for cryptococcal infections, coccidioidomycosis, selected cases of blastomycosis and histoplasmosis, and superficial fungal infections such as tinea, pityriasis versicolor, and onychomycosis.

Mechanism: Fluconazole selectively inhibits fungal 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane formation, resulting in inhibition of fungal growth.
Drug Class: Triazole antifungal.
Clinical Use: Treatment and prevention of systemic and superficial fungal infections.

Specification

Generic Name	Fluconazole Capsules
Brand Name	DIFLUCAN®
Ingredient	Fluconazole
Dosage Form	Capsule
Package	150 mg/capsule, 1 capsule/carton
Conditions Treated	Vulvovaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, disseminated candidiasis, cryptococcosis, coccidioidomycosis, blastomycosis, histoplasmosis, tinea infections, pityriasis versicolor, onychomycosis
Taboos	Hypersensitivity to fluconazole or other azole antifungals; concomitant use with cisapride, halofantrine, or other QT-prolonging drugs contraindicated in labeling
Place of origin	China
Prescription type	Prescription Only (Rx)
Storage Conditions	Store tightly closed in a cool, dry place away from heat and moisture.
Manufacturer	Viatris Pharmaceuticals (DALIAN) Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H10960164
Approval Date	April 14, 2025
Shelf Life	60 months

How to use ?

Recommended Dose: Dosage varies depending on the infection. For uncomplicated vulvovaginal candidiasis, take 150 mg orally as a single dose. Other fungal infections require different dosing schedules and treatment durations as prescribed by a healthcare professional.

Time: May be taken with or without food. Swallow the capsule whole with water.

Instructions for use: Take exactly as prescribed and complete the full treatment course, even if symptoms improve early. Patients receiving long-term therapy may require periodic monitoring of liver and kidney function.

Interaction: Fluconazole inhibits CYP450 enzymes and may increase blood levels of medications such as warfarin, statins, sulfonylureas, cyclosporine, and tacrolimus. Rifampicin and other enzyme inducers may reduce fluconazole effectiveness. Avoid concomitant use with medications that significantly prolong the QT interval.

Side effects: Common adverse reactions include headache, nausea, abdominal pain, diarrhea, vomiting, rash, and mild elevations of liver enzymes. Rare but serious reactions include severe liver injury, QT prolongation, torsades de pointes, Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), severe hypersensitivity reactions, and blood dyscrasias.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What is DIFLUCAN® used for?

DIFLUCAN® is used to treat Candida infections, cryptococcal infections, and various superficial and systemic fungal infections, including vaginal yeast infections.

How is vaginal yeast infection treated with DIFLUCAN®?

For uncomplicated vulvovaginal candidiasis, the usual adult dose is one 150 mg capsule taken orally as a single dose, unless otherwise directed by a physician.

Can I take DIFLUCAN® with food?

Yes. Food does not affect the absorption of fluconazole, so it may be taken with or without meals.

Does DIFLUCAN® (Fluconazole Capsules) interact with other medicines?

Yes. Fluconazole may interact with warfarin, statins, certain antidiabetic agents, immunosuppressants, and other medications. Inform your healthcare provider about all medicines you are taking before starting treatment.