Description
Indication & Scope
Benzylpenicillin Sodium for Injection is a prescription natural penicillin antibiotic indicated for the treatment of susceptible infections caused by streptococci, pneumococci, non-penicillinase-producing staphylococci, Neisseria meningitidis, spirochetes, and Actinomyces. It is also used for syphilis, leptospirosis, tetanus, anthrax, actinomycosis, infective endocarditis, septicemia, meningitis, pneumonia, and other susceptible infections.
- Mechanism: Benzylpenicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in bacterial cell lysis.
- Drug class: Natural β-lactam penicillin antibiotic.
- Clinical use: First-line treatment for susceptible streptococcal infections, meningococcal disease, syphilis, and other penicillin-sensitive bacterial infections.
| Generic Name | Benzylpenicillin Sodium for Injection |
| Brand Name | CSPC® |
| Ingredient | Benzylpenicillin Sodium (Penicillin G Sodium) |
| Dosage Form | Injection |
| Package | 0.48 g (800,000 IU)/vial, 50 vials/box |
| Conditions Treated | Streptococcal infections, pneumonia, meningitis, septicemia, infective endocarditis, syphilis, leptospirosis, tetanus, anthrax, actinomycosis and other susceptible bacterial infections |
| Taboos | Hypersensitivity to penicillins or β-lactam antibiotics; positive penicillin skin test |
| Place of origin | China |
| Prescription type | Prescription Drug (Rx) |
| Storage Conditions | Store below 20°C in a dry place, protected from light. Reconstituted solution should be used immediately. |
| Manufacturer | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval Number | H13021634 |
| Approval Date | July 8, 2024 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: Administer by intramuscular injection or intravenous infusion. The dosage depends on the type and severity of infection. Adults generally receive 0.8–20 million IU daily in divided doses.
Time: Reconstitute immediately before administration. Infuse intravenously at the recommended rate. Do not administer by rapid IV injection.
Instructions for use: A penicillin skin test is required before use. Use freshly prepared solution and complete the full prescribed course of therapy.
Interaction: Avoid mixing with erythromycin, clindamycin, tetracyclines, or alkaline solutions. Probenecid may increase penicillin plasma concentrations.
Side effects: Common adverse reactions include allergic reactions, rash, injection-site pain, nausea, diarrhea, and rarely anaphylactic shock, neurotoxicity, or antibiotic-associated colitis.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What infections can Benzylpenicillin Sodium treat?
It is indicated for susceptible infections including streptococcal infections, pneumonia, meningitis, septicemia, infective endocarditis, syphilis, leptospirosis, tetanus, anthrax, and actinomycosis.
Is a skin test required before administration?
Yes. A penicillin skin test should be performed before treatment according to approved prescribing recommendations.
Can it treat penicillin-resistant bacteria?
No. It is ineffective against penicillinase-producing staphylococci and many Gram-negative organisms, including Pseudomonas aeruginosa.
What is the most important safety concern?
Severe allergic reactions, including anaphylaxis, may occur. Emergency treatment facilities should be available during administration.
CSPC® | Benzylpenicillin Sodium | Bacterial Infections | DengYueRX
INN: Benzylpenicillin Sodium
Indications: Susceptible bacterial infections
Dosage Form: Powder for Injection
Strength: 0.48 g (800,000 IU)
Original price was: $6.00.$5.00Current price is: $5.00.
