Description
Indication & Scope
- Mechanism
Ainuovirine is a non-nucleoside reverse transcriptase inhibitor that allosterically inhibits HIV-1 reverse transcriptase; lamivudine and tenofovir disoproxil fumarate are nucleoside reverse transcriptase analogues that compete for incorporation into viral DNA and terminate chain elongation. The three components act synergistically to block multiple steps of HIV-1 replication and lower peripheral blood viral load. - Drug class
Oral fixed-dose combination antiretroviral medicine, compound preparation consisting of NNRTI and NRTIs for HIV-1 infection. - Clinical use
Multi-center clinical trials demonstrate durable viral suppression, a high genetic barrier to drug resistance and well-tolerated safety profile; administered orally once daily without food restriction. It is an independently developed domestic single-pill triple regimen for HIV-1 treatment-naive adults.
| Generic Name | Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate Tablets |
| Brand Name | FuBangDe® |
| Ingredient | Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate |
| Dosage Form | Film-coated Tablets |
| Package | 0.15g:0.3g:0.3g (Ainuovirine:Lamivudine ：Tenofovir Disoproxil ）* 30 tablets / bottle |
| Conditions Treated | The treatment of HIV-1 infection in treatment-naive adult patients |
| Taboos | Patients with hypersensitivity to any active ingredients or excipients contained in this product |
| Place of origin | Jiangsu, China |
| Priscription Type | Prescription drug (Rx) |
| Storage Conditions | Seal and store below 30℃, keep away from moisture |
| Manufacturer | Jiangsu Aidea Pharmaceutical Group Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | H20220033 |
| Date of Revision | June 20, 2025 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: One tablet taken orally once daily, with or without food. Do not miss doses; if a dose is missed within 12 hours, take it immediately and resume regular schedule.
Time: Administer routinely at the same time each day for continuous suppression of HIV-1 viral load. Long-term daily administration is required for sustained therapeutic effect.
Interaction: Avoid co-administration with drugs that induce liver enzymes. Concomitant use of other anti-HIV agents needs professional medical guidance. Do not adjust dosage arbitrarily without physician’s advice.
Side effects: Mostly mild to moderate gastrointestinal discomfort, dizziness, abnormal dreams, fatigue and abnormal lipid parameters. Rare severe liver injury, renal adverse reactions and hypersensitivity; severe systemic allergic reactions are extremely uncommon.
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
Which is better, TDF or Taf?
TDF is generally safe and well tolerated, but it can cause kidney problems and bone loss in some people. Taf has less effect on the kidneys and bones.
Is tenofovir disoproxil fumarate and lamivudine used as PrEP?
For PrEP and PEP to lower HIV-1 infection risk: Lamivudine and tenofovir disoproxil shall only be applied within integrated prevention regimens with additional protective interventions.
What should I avoid while taking lamivudine?
Its low resistance barrier, alongside later emergence of stronger, more effective drugs with higher genetic barriers to resistance
Does lamivudine affect kidney function?
Studies showed lamivudine concentrations rise as renal function declines.
FuBangDe®Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate Tablets | HIV-1 | DengYueRX
INN: Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate
Indications: HIV-1
Dosage Form: Film-coated Tablets
Strength: 0.15g:0.3g:0.3g（ Ainuovirine： Lamivudine ：Tenofovir Disoproxil ）/ tablet
