Description
Indication & Scope
Xofluza® Baloxavir Marboxil Tablets treats acute uncomplicated influenza A and B in patients aged 12 years and older with symptom onset within 48 hours; post-exposure prophylaxis of influenza for high-risk populations after close contact with confirmed influenza cases.
- Mechanism: Inhibits cap-dependent endonuclease of influenza virus polymerase complex, blocks viral mRNA transcription at the early stage of replication to stop virus proliferation.
- Drug class: Cap-dependent endonuclease inhibitor; anti-influenza small-molecule antiviral agent.
- Clinical use: Rapid one-dose antiviral therapy for acute influenza to shorten symptom duration and reduce complication risks; preventive use for exposed high-risk groups to lower infection probability.
| Generic Name | Baloxavir Marboxil Tablets |
| Brand Name | Xofluza |
| Ingredient | Baloxavir Marboxil |
| Dosage Form | Tablets |
| Package | 20mg*2 tablets/box;
40mg*1 tablet/box; 40mg*2 tablets/box |
| Conditions Treated | Acute influenza A/B infection in adolescents and adults; influenza exposure prophylaxis for vulnerable crowds |
| Taboos | Severe hypersensitivity to baloxavir marboxil or tablet excipients |
| Place of origin | (1)2-5-1, Mishima, Settsu, Osaka 566-0022, Japan；(2)3300 Marshall Avenue, Norman, Oklahoma (OK) 73072, USA |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed blister packs stored at 15°C–30°C, dry and away from direct sunlight |
| Manufacturer | (1)Shionogi Pharma Co., Ltd.;
(2)Avara Pharmaceutical Technologies, Inc. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20210027; HJ20210028 |
| Approval Date | Jan 4, 2026 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: Weight ≥40kg: single 40mg oral dose; weight <40kg: single 20mg oral dose.
Time: Taken once within 48 hours of the first appearance of influenza symptoms, independent of meals.
Instructions for use: Swallow whole tablets with water, do not crush or chew; complete the single dose without supplementary medication even if symptoms ease quickly.
Interaction: Polyvalent cations including iron, calcium and magnesium reduce absorption when taken simultaneously; separate administration by at least 4 hours.
Side effects:
1. Common: mild diarrhea, nausea, headache, sore throat.
2. Rare severe: severe allergic reactions, transient elevated liver enzymes.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What two main therapeutic purposes are covered in the approved indications for Baloxavir Marboxil Tablets?
The medicine treats acute influenza infection and provides post-exposure preventive protection against influenza for high-risk groups.
What time limit must be followed for administration to guarantee optimal antiviral efficacy of Baloxavir Marboxil Tablets this single-dose influenza drug?
Administration must be finished within 48 hours after the first emergence of influenza symptoms.
What is the core difference in antiviral mechanism between Baloxavir Marboxil Tablets and neuraminidase inhibitor anti-influenza preparations?
It blocks early viral mRNA transcription, while neuraminidase inhibitors only prevent mature virus release from infected cells.
What population weight standard determines the two different single-dose specifications for Baloxavir Marboxil Tablets?
A weight threshold of 40 kilograms separates the 20mg and 40mg single dosage regimens.
Xofluza® | Baloxavir Marboxil Tablets | Influenza A and B | DengYueRX
INN: Baloxavir Marboxil Tablets
Indications: Influenza A and B
Dosage Form: Tablets
Strength: 20mg/tablet
Original price was: $47.65.$40.50Current price is: $40.50.
