Description
Indication & Scope
Gemcitabine Hydrochloride for Injection (Gemzar®) is a pyrimidine antimetabolite cytotoxic drug. After intracellular phosphorylation, it competes with deoxycytidine to incorporate into tumor cell DNA, blocks DNA chain extension and replication, induces tumor cell apoptosis and inhibits tumor growth.
- Mechanism
Pyrimidine antimetabolite DNA synthesis inhibitor - Drug class
Prescription injectable cytotoxic chemotherapy drug - Clinical use
Non-small cell lung cancer, pancreatic cancer, bladder cancer
| Generic Name | Gemcitabine Hydrochloride for Injection |
| Brand Name | Gemzar® |
| Ingredient | Gemcitabine Hydrochloride |
| Dosage Form | Injection |
| Package | 200mg/vial |
| Conditions Treated | Combined with cisplatin for inoperable locally advanced or metastatic bladder cancer; Adjuvant chemotherapy for stage IIA-IIB and III pancreatic cancer after radical resection |
| Taboos | Patients with severe hypersensitivity to gemcitabine or any excipients |
| Place of origin | Pallini Attiki, Greece |
| Priscription Type | Prescription Drug |
| Storage Conditions | Sealed, store below 30°C, protected from light |
| Manufacturer | Vianex S.A.-Plant C |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | HJ20160224 |
| Approval Date | December 28, 2022 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Standard dosage regimen for NSCLC monotherapy: 1250 mg/m² intravenous infusion over 30 minutes on Day 1 and Day 8 of each 21-day cycle.
Time: Two mainstream cycles: 21-day cycle (Day1,8 administration) and 28-day cycle (Day1,8,15 administration); infusion lasts strictly 30 minutes, prolonged infusion increases toxicity risk.
Interaction: CoRadiotherapy combined use may induce severe radiation toxicity, interval separation is needed. mbined with platinum drugs will aggravate myelosuppression, regular blood routine monitoring required.
Side effects: Common reactions: Neutropenia, thrombocytopenia, anemia, fever, fatigue, nausea, vomiting, elevated liver transaminase, rash, dyspnea.
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is the core anti-tumor mechanism of gemcitabine?
It competes with deoxycytidine to block tumor DNA replication and trigger cell apoptosis.
What adjuvant therapy indication does Gemzar have for pancreatic cancer?
Adjuvant chemotherapy for stage IIA-IIB and III pancreatic cancer after radical resection.
Why can’t gemcitabine be infused rapidly within less than 30 minutes?
Shortened infusion time will sharply raise the risk of severe systemic toxicity.
What class of chemotherapy drug is gemcitabine hydrochloride?
It belongs to pyrimidine antimetabolite DNA synthesis inhibitor.
Gemzar® | Gemcitabine Hydrochloride for Injection | NSCLC | DengYueRX
INN: Gemcitabine Hydrochloride
Indications: NSCLC (non-small cell lung cancer)
Dosage Form: Injection
Strength: 0.2g/Vial
Original price was: $68.68.$58.38Current price is: $58.38.
Low MOQ
WHO-GMP
Worldwide Delivery
Compliance and Regulatory Documents
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