Home - Prescription Medicines - ZOCOR® | Simvastatin | High Cholesterol | DengYueRX
Description
Indication & Scope
ZOCOR® is a prescription HMG-CoA reductase inhibitor (statin) indicated as an adjunct to diet for reducing elevated total cholesterol, LDL cholesterol, triglycerides, and apolipoprotein B in patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia, mixed dyslipidemia, and homozygous familial hypercholesterolemia. It is also indicated for reducing the risk of major cardiovascular events in patients with coronary heart disease or those at high cardiovascular risk.
- Mechanism: Simvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol biosynthesis, resulting in increased LDL receptor expression and enhanced clearance of circulating LDL cholesterol.
- Drug class: HMG-CoA reductase inhibitor (Statin).
- Clinical use: Treatment of hypercholesterolemia and mixed dyslipidemia, and prevention of myocardial infarction, stroke, coronary revascularization, and progression of atherosclerotic cardiovascular disease.
| Generic Name | Simvastatin Tablets |
| Brand Name | ZOCOR® |
| Ingredient | Simvastatin |
| Dosage Form | Tablet |
| Package | 20 mg/tablet, 7 tablets/carton |
| Conditions Treated | Primary hypercholesterolemia, mixed dyslipidemia, familial hypercholesterolemia, coronary heart disease |
| Taboos | Hypersensitivity to simvastatin; active liver disease; persistent unexplained elevations of hepatic transaminases; pregnancy; breastfeeding |
| Place of origin | United Kingdom |
| Prescription type | Prescription Drug (Rx) |
| Storage Conditions | Store in a tightly closed container at room temperature, protected from moisture and light. |
| Manufacturer | Organon Pharma (UK) Limited |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval Number | HJ20171161 |
| Approval Date | March 21, 2022 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: For hypercholesterolemia, the usual starting dose is 10–20 mg once daily in the evening. Patients requiring greater LDL-C reduction may start at 20–40 mg daily. The maximum recommended dose is 40 mg once daily.
Time: Take once daily in the evening, with or without food.
Instructions for use: Swallow the tablet whole or split if needed. Continue a cholesterol-lowering diet during treatment. Dose adjustments should be based on lipid response.
Interaction: Avoid strong CYP3A4 inhibitors, gemfibrozil, cyclosporine, danazol, large amounts of grapefruit juice, and other medicines that increase the risk of myopathy or rhabdomyolysis.
Side effects: Common adverse reactions include myalgia, abdominal pain, constipation, nausea, headache, elevated liver enzymes, and muscle weakness. Rare but serious reactions include myopathy and rhabdomyolysis.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is ZOCOR® used for?
It is used to lower cholesterol and reduce the risk of heart attack, stroke, and other cardiovascular events.
When should I take ZOCOR®?
It is generally taken once daily in the evening.
Can I drink grapefruit juice while taking ZOCOR®?
No. Grapefruit juice may significantly increase simvastatin levels and the risk of serious muscle injury.
Is ZOCOR® a prescription medicine?
Yes. It is available only with a prescription.
ZOCOR® | Simvastatin | High Cholesterol | DengYueRX
INN: Simvastatin
Indications: Hypercholesterolemia
Dosage Form: Tablet
Strength: 20 mg/Tablet
$4.87 Original price was: $4.87.$4.14Current price is: $4.14.