Description
Indication & Scope
Ganagliflozin Proline Tablets helps to adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- Mechanism: SGLT-2 inhibitor; blocks renal sodium-glucose cotransporter 2 to reduce glucose reabsorption, inducing urinary glucose excretion and lowering blood glucose.
- Drug class: Sodium-glucose co-transporter 2 (SGLT-2) inhibitor, oral antidiabetic.
- Clinical use: Monotherapy or combination with metformin to lower HbA1c, reduce blood pressure and weight in T2DM adults.
| Generic Name | Ganagliflozin Proline Tablets |
| Brand Name | HuiYouJing |
| Ingredient | Ganagliflozin Proline Tablets |
| Dosage Form | Tablets |
| Package | 25 mg*7 tablets/box |
| Conditions Treated | Adult type 2 diabetes mellitus |
| Taboos | 1. Hypersensitivity to ganagliflozin or tablet excipients
2. Type 1 diabetes, diabetic ketoacidosis 3. Severe renal impairment (eGFR <45 mL/min/1.73m²) 4. Pregnant or breastfeeding women |
| Place of origin | China |
| Prescription type | Prescription-only |
| Storage Conditions | Store tightly sealed below 30°C, avoid humidity and direct sunlight |
| Manufacturer | HuiSheng Biopharmaceutical Co., Ltd |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20240002 |
| Date of Revision | 2024 |
| Shelf Life | 18 months |
How to use ?
Recommended Dose: 5 mg oral once daily; maximum 10 mg daily if glycemic control insufficient.
Time: Administer in the morning, with or without meals.
Instructions for use:
1. Swallow whole tablet with water; no crushing.
2. Maintain adequate daily water intake to prevent dehydration.
3. Monitor renal function before and during treatment.
4. Discontinue if genital/urinary severe infection occurs.
Interaction:
1. Diuretics increase dehydration and hypotension risk.
2. Insulin/sulfonylureas raise hypoglycemia risk (dose reduction required).
3. CYP3A4 modulators have minimal impact on drug exposure.
Side effects:
1. Common: Genital mycotic infection, polyuria, thirst, fatigue, hypotension.
2. Severe: Diabetic ketoacidosis, acute kidney injury, Fournier’s gangrene, hypovolemia.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is Ganagliflozin Proline pharmacokinetic half-life, and how does this affect dosing frequency?
It has a long half-life (~12–16 hours), supporting once-daily dosing, with sustained glucose-lowering effect throughout the day.
What is the primary mechanism by which Ganagliflozin Proline reduces blood glucose levels?
It inhibits sodium-glucose cotransporter 2 in the renal proximal tubule, reducing glucose reabsorption and increasing urinary glucose excretion.
What common metabolic adverse effects should patients be monitored for with Ganagliflozin Proline?
Genital mycotic infections, volume depletion, and euglycemic diabetic ketoacidosis.
In which patient groups is Ganagliflozin Proline contraindicated?
Patients with severe renal impairment, type 1 diabetes, or history of diabetic ketoacidosis.
HuiYouJing® | Ganagliflozin Proline Tablets | Diabetes | DengYueRX
INN: Ganagliflozin Proline
Indications: Adjunct to improve glycemic control in adults with type 2 diabetes mellitus.
Dosage Form: Tablets
Strength: 25 mg*7 tablets/package
