Description
Indication & Scope
Betaloc ZOK® (Metoprolol Succinate Sustained-release Tablets) is applied for the treatment of hypertension, angina pectoris, chronic heart failure and arrhythmia, with the effects of slowing heart rate and reducing myocardial oxygen consumption.
- Mechanism: Selectively blocks beta-1 adrenergic receptors of the heart, inhibits sympathetic nerve excitation, slows heart rate, reduces cardiac contractility and myocardial oxygen consumption, and stabilizes cardiac electrical activity.
- Drug class: Selective beta-1 adrenergic receptor blocker.
- Clinical use: Widely used in cardiovascular department for long-term control of hypertension, relief of angina pectoris symptoms, standardized treatment of chronic heart failure and correction of benign arrhythmia.
| Generic Name | Metoprolol Succinate Sustained-release Tablets |
| Brand Name | Betaloc ZOK® |
| Ingredient | Metoprolol Succinate |
| Dosage Form | Tablets |
| Package | 47.5 mg* 7 tablets/box
47.5 mg* 28 tablets/box |
| Conditions Treated | Hypertension, angina pectoris, chronic heart failure, cardiac arrhythmia |
| Taboos | Contraindicated in patients with severe bradycardia, atrioventricular block, cardiogenic shock, severe heart failure and allergic constitution to metoprolol |
| Place of origin | Gartunavagen, SE-152 57 Sodertalje, Sweden |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed storage at room temperature, keep away from moisture and direct sunlight |
| Manufacturer | AstraZeneca AB |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20140780 |
| Approval Date | Dec 20, 2023 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Initial dose for hypertension and angina pectoris is 47.5 mg once daily, and the dose can be gradually increased according to disease conditions.
Time: Once daily, taken at a fixed time every day.
Instructions for use: Take orally with whole tablet swallowed, do not crush or chew the sustained-release tablet, can be taken with or without food.
Interaction: Combined use with non-dihydropyridine calcium channel blockers may aggravate bradycardia; combined with hypoglycemic drugs may mask hypoglycemia symptoms.
Side effects: Fatigue, dizziness, bradycardia, limb coldness; occasional gastrointestinal discomfort and sleep disorders.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What cardiovascular symptoms and diseases can Metoprolol Succinate Sustained-release Tablets treat?
The drug treats hypertension, angina pectoris, chronic heart failure and arrhythmia, and relieves symptoms caused by excessive myocardial oxygen consumption.
Which patients are not suitable for taking Metoprolol Succinate Sustained-release Tablets?
Patients with severe bradycardia, atrioventricular block, cardiogenic shock and severe heart failure are prohibited from use.
What is the main pharmacological effect of Metoprolol Succinate Sustained-release Tablets?
It slows heart rate, reduces myocardial oxygen consumption, stabilizes heart rhythm and controls elevated blood pressure.
What common physical discomforts may occur after long-term use of Metoprolol Succinate Sustained-release Tablets?
Common adverse reactions include fatigue, dizziness, slow heart rate and cold limbs, and occasional stomach discomfort and poor sleep.
Betaloc ZOK® | Metoprolol Succinate Sustained-release Tablets | Hypertension/Angina Pectoris/Chronic Heart Failure/Arrhythmia | DengYueRX
INN: Metoprolol Succinate
Indications: Hypertension, angina pectoris, chronic heart failure and arrhythmia
Dosage Form: Tablets
Strength: 47.5 mg/Tablet
Price range: $2.94 through $11.18
