glucophage xr metformin hydrochloride extended release tablet 0

Description

Indication & Scope

Glucophage XR® is a prescription biguanide antihyperglycemic agent indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. The prolonged-release formulation provides sustained drug release with improved gastrointestinal tolerability compared with immediate-release metformin. It may be used as monotherapy or in combination with other antidiabetic agents, including sulfonylureas, DPP-4 inhibitors, SGLT-2 inhibitors, GLP-1 receptor agonists, and insulin.

Mechanism: Metformin decreases hepatic glucose production, improves insulin sensitivity, and reduces intestinal glucose absorption without stimulating insulin secretion.
Drug class: Biguanide antihyperglycemic agent.
Clinical use: First-line pharmacologic treatment for adults with type 2 diabetes mellitus, either alone or in combination with other glucose-lowering therapies.

Specification

Generic Name	Metformin Hydrochloride Extended-release Tablets
Brand Name	Glucophage XR®
Ingredient	Metformin Hydrochloride
Dosage Form	Extended-release Tablet
Package	0.5 g/tablet, 30 tablets/carton
Conditions Treated	Adults with type 2 diabetes mellitus requiring improved glycemic control as an adjunct to diet and exercise, either as monotherapy or in combination with other antidiabetic medications.
Taboos	Hypersensitivity to metformin; severe renal impairment; metabolic acidosis, including diabetic ketoacidosis; severe hepatic impairment.
Place of origin	China
Prescription type	Prescription Drug (Rx)
Storage Conditions	Store below 30°C in a dry place, protected from moisture.
Manufacturer	Merck Pharmaceutical Manufacturing (Jiangsu) Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H20227043
Approval Date	March 30, 2022
Shelf Life	36 months

How to use ?

Recommended Dose: Start with 500 mg once daily with the evening meal. Increase gradually according to glycemic response. The maximum recommended daily dose is 2,000 mg.

Time: Take once daily with food, preferably the evening meal.

Instructions for use: Swallow the tablet whole. Do not crush, chew, or split the tablet. Continue diet and exercise throughout treatment.

Interaction: Avoid excessive alcohol. Temporarily discontinue before and after iodinated contrast procedures. Insulin or sulfonylureas may increase the risk of hypoglycemia.

Side effects: Common adverse reactions include nausea, diarrhea, abdominal discomfort, decreased appetite, and metallic taste. Long-term use may reduce vitamin B12 levels.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support