Description
Indication & Scope
YuanSiTan® Losartan Potassium and Hydrochlorothiazide Tablets treats essential hypertension with poor blood pressure control by single antihypertensive drug monotherapy.
- Mechanism: Losartan potassium blocks angiotensin II receptors to dilate blood vessels; hydrochlorothiazide exerts diuretic and sodium excretion effects to reduce blood volume. The two ingredients work synergistically to lower blood pressure through dual pathways.
- Drug class: Compound antihypertensive drug (ARB + thiazide diuretic).
- Clinical use: Combined antihypertensive therapy for patients with unsatisfactory blood pressure control via single-drug treatment.
| Generic Name | Losartan Potassium and Hydrochlorothiazide Tablets |
| Brand Name | YuanSiTan |
| Ingredient | Losartan Potassium and Hydrochlorothiazide |
| Dosage Form | Tablets |
| Package | Losartan Potassium 100mg + Hydrochlorothiazide 25mg*7 tablets/box;
Losartan Potassium 50mg + Hydrochlorothiazide 12.5mg*7 tablets/box |
| Conditions Treated | Refractory essential hypertension unresponsive to single antihypertensive monotherapy |
| Taboos | Hypersensitivity to losartan, hydrochlorothiazide or formulation excipients; severe renal and hepatic insufficiency; severe electrolyte disturbance; pregnancy |
| Place of origin | China |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed storage at room temperature, avoid humidity, high temperature and direct sunlight |
| Manufacturer | Lepu Pharmaceuticals, Inc. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20123367; H20217082 |
| Approval Date | Jul 18, 2022 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: One tablet once daily for routine hypertension maintenance treatment.
Time: Once daily, fixed administration time regardless of meals.
Instructions for use: Swallow whole with water, continuous long-term administration is required for stable blood pressure control, dosage adjustment follows medical advice.
Interaction: Combination with other antihypertensive drugs enhances hypotensive effect; concurrent potassium supplements cause hyperkalemia risk; NSAIDs affect renal function.
Side effects:
1. Common: mild dizziness, fatigue, dry mouth, electrolyte fluctuation.
2. Rare: hypotension, photosensitivity reaction, hepatic and renal function abnormality.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What kind of hypertension condition requires Losartan Potassium and Hydrochlorothiazide Tablets?
It is suitable for essential hypertension that cannot be well controlled by single antihypertensive drugs.
What dual mechanisms achieve the antihypertensive effect of Losartan Potassium and Hydrochlorothiazide Tablets?
It lowers blood pressure via vascular dilation and diuretic sodium excretion dual synergistic pathways.
What severe organ dysfunction prohibits the use of Losartan Potassium and Hydrochlorothiazide Tablets?
Severe renal insufficiency and severe hepatic insufficiency are absolute contraindications for administration.
What electrolyte problem may occur during long-term medication of Losartan Potassium and Hydrochlorothiazide Tablets?
Mild electrolyte disturbance may occur and requires regular body electrolyte monitoring.
YuanSiTan® | Losartan Potassium and Hydrochlorothiazide Tablets | Essential Hypertension | DengYueRX
INN: Losartan Potassium and Hydrochlorothiazide Tablets
Indications: Essential hypertension
Dosage Form: Tablets
Strength: Losartan Potassium 100mg + Hydrochlorothiazide 25mg/tablet
Original price was: $2.07.$1.76Current price is: $1.76.
