actIns pioglitazone hydrochloride tablet 15mg per tablet 7tablets per blister 2blisters per carton

Description

Indication & Scope

ActIns® is a prescription thiazolidinedione (TZD) insulin sensitizer indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It may be used as monotherapy or in combination with metformin, sulfonylureas, or insulin when additional glycemic control is required. It is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Mechanism: Pioglitazone is a selective peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist that improves insulin sensitivity in adipose tissue, skeletal muscle, and the liver, thereby reducing insulin resistance and hepatic glucose production.
Drug Class: Thiazolidinedione (TZD) insulin sensitizer.
Clinical Use: Improvement of glycemic control in adults with type 2 diabetes mellitus as monotherapy or in combination with other antidiabetic agents.

Specification

Generic Name	Pioglitazone Hydrochloride Tablets
Brand Name	ActIns®
Ingredient	Pioglitazone Hydrochloride
Dosage Form	Tablet
Package	15 mg/tablet, 14 tablets/carton (7 tablets × 2 blisters)
Conditions Treated	Glycemic control in adults with type 2 diabetes mellitus
Taboos	Hypersensitivity to pioglitazone or any component of the product; NYHA Class III or IV heart failure; type 1 diabetes mellitus; diabetic ketoacidosis; active liver disease
Place of origin	China
Prescription type	Prescription Drug (Rx)
Storage Conditions	Store below 30°C in a dry place, protected from light.
Manufacturer	Beijing Taiyang Pharmaceutical Industry Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H20040267
Approval Date	July 4, 2025
Shelf Life	24 months

How to use ?

Recommended Dose: The recommended starting dose is 15–30 mg once daily. The dose may be increased to a maximum of 45 mg once daily according to glycemic response.

Time: Take once daily, with or without food.

Instructions for use: Swallow the tablet whole with water. It may be used alone or in combination with other antidiabetic medications. Regular monitoring of blood glucose and liver function is recommended.

Interaction: The glucose-lowering effect may be enhanced when combined with insulin or sulfonylureas, increasing the risk of hypoglycemia. CYP2C8 inhibitors (e.g., gemfibrozil) may increase pioglitazone exposure, while CYP2C8 inducers (e.g., rifampin) may reduce its effectiveness.

Side effects: Common adverse reactions include edema, weight gain, headache, upper respiratory tract infection, and anemia. When used with insulin or sulfonylureas, hypoglycemia may occur. Serious adverse reactions include heart failure, hepatic dysfunction, macular edema, and increased fracture risk.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What is ActIns®(Pioglitazone Hydrochloride Tablets) used for?

It is used to improve blood glucose control in adults with type 2 diabetes mellitus.

Can ActIns®(Pioglitazone Hydrochloride Tablets) be used alone?

Yes. It may be used as monotherapy or in combination with other antidiabetic medicines.

Should ActIns®(Pioglitazone Hydrochloride Tablets) be taken with food?

It can be taken with or without food at the same time each day.

Who should not use ActIns®(Pioglitazone Hydrochloride Tablets)?

Patients with type 1 diabetes, diabetic ketoacidosis, NYHA Class III or IV heart failure, active liver disease, or hypersensitivity to pioglitazone should not use this medicine.