Description
Indication & Scope
Coniel® Benidipine Hydrochloride Tablets indicates for the clinical treatment of adult essential hypertension and angina pectoris caused by coronary heart disease.
- Mechanism: Benidipine hydrochloride is a triple calcium channel blocker that blocks calcium channels of vascular smooth muscle, cardiac muscle and sympathetic nerve endings. It dilates peripheral blood vessels to reduce blood pressure, dilates coronary arteries to increase myocardial blood perfusion, relieves coronary spasm, and improves myocardial ischemia and angina symptoms.
- Drug class: Triple-action Dihydropyridine Calcium Channel Blocker (CCB).
- Clinical use: Clinically widely used for long-term stable control of essential hypertension and symptomatic relief and long-term prevention of coronary heart disease angina pectoris, with dual antihypertensive and anti-anginal clinical value.
| Generic Name | Benidipine Hydrochloride Tablets |
| Brand Name | Coniel® |
| Ingredient | Benidipine Hydrochloride |
| Dosage Form | Tablets |
| Package | 8mg*7 tablets/box;
8mg*70 tablets/box; 4mg*7 tablets/box; 4mg*70 tablets/box; |
| Conditions Treated | Essential hypertension, coronary heart disease-induced angina pectoris |
| Taboos | Contraindicated in patients with hypersensitivity to benidipine hydrochloride or drug excipients, severe hypotension, and pregnant women. Use with extreme caution in patients with severe heart failure |
| Place of origin | 2547-3 Oaza Fujimagari, Ube-shi, Yamaguchi, Japan |
| Prescription type | Prescription-only |
| Storage Conditions | Store sealed at room temperature (10°C-25°C), keep dry, avoid high temperature, humidity and direct sunlight irradiation |
| Manufacturer | Kyowa Kirin Co., Ltd. Ube Plant |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20170109; HJ20170111 |
| Approval Date | Jan 20, 2022 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: For hypertension: 2mg-4mg once daily, adjustable according to blood pressure response. For angina pectoris: 4mg once or twice daily, individualized adjustment.
Time: Take orally once daily in the morning or twice daily at fixed morning and evening time, independent of meals.
Instructions for use: Swallow the tablet whole with water. Start with low dose and adjust gradually. Avoid sudden drug withdrawal during long-term medication.
Interaction: Combined with other antihypertensive drugs significantly enhances hypotensive effect. Concomitant use with anti-anginal drugs enhances myocardial ischemia relief efficacy. Combined with grapefruit juice will increase blood drug concentration and cause adverse reactions.
Side effects:
1. Common side effects include facial flushing, dizziness, headache, peripheral edema and palpitations.
2. Rare adverse reactions include gastrointestinal discomfort, abnormal liver function and allergic skin rash.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What two cardiovascular problems can Benidipine Hydrochloride Tablets treat?
It can treat essential hypertension and relieve angina symptoms caused by coronary heart disease.
What food should be avoided during medication period of Benidipine Hydrochloride Tablets?
Grapefruit and grapefruit juice should be avoided to prevent excessive drug concentration in blood.
What mild physical reactions may occur after taking Benidipine Hydrochloride Tablets?
Mild facial flushing, dizziness, limb edema and slight palpitations may appear individually.
Can the dosage of Benidipine Hydrochloride Tablets be increased arbitrarily when blood pressure is unstable?
Dosage adjustment must follow medical advice, and arbitrary dose increase is forbidden.
Coniel® | Benidipine Hydrochloride Tablets | Essential Hypertension/Angina Pectoris | DengYueRX
INN: Benidipine Hydrochloride Tablets
Indications: Essential hypertension, angina pectoris
Dosage Form: Tablets
Strength: 8mg/tablet
Original price was: $10.03.$8.53Current price is: $8.53.
