Description

Indication & Scope

Voriconazole suppresses fungal cytochrome P450 enzyme to block ergosterol synthesis, destroy fungal cell membrane. It shows strong activity against Aspergillus, resistant Candida and rare mould fungi.

Mechanism
Triazole antifungal agent
Drug class
Systemic injectable antifungal
Clinical use
Second-generation triazole antifungal with broad spectrum, mainly applied to immunocompromised patients with severe invasive mycosis.

Specification

Generic Name	Voriconazole For Injection
Brand Name	Vfend®
Ingredient	Voriconazole
Dosage Form	Injection
Package	0.2g/vial/box
Conditions Treated	For serious invasive fungal infections caused by Candida, Aspergillus and other sensitive fungi: fungemia, pulmonary aspergillosis, invasive candidiasis, central nervous system fungal infection.
Taboos	Patients hypersensitive to voriconazole or excipients of this product are prohibited from use. Concomitant use with certain CYP3A4 substrates is forbidden.
Place of origin	USA
Priscription Type	Prescription Drug
Storage Conditions	Sealed, store below 30°C, protected from light
Manufacturer	Pharmacia & Upjohn Company LLC
Registration Authority	National Medical Products Administration (NMPA)
Approval number	HJ20181102
Approval Date	October 25, 2022
Shelf Life	36 months

How to use ?

Recommended Dose: Intravenous infusion after reconstitution and dilution. Loading dose on the first two days, then maintenance dose daily.

Time: Infuse twice daily in the initial stage, switch to once daily maintenance treatment.

Interaction: Multiple interactions with immunosuppressants, statins and antiarrhythmic drugs; blood drug concentration monitoring is required.

Side effects: Visual disturbance, liver enzyme elevation, fever, headache.

Important Notice

This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What should I avoid while using voriconazole?

Avoid direct sunlight.

When to stop voriconazole?

Before the infection is completely cleared.

What is the age limit for voriconazole?

In children aged 2 to <12.

Is hair loss a side effect of it?

Hair loss on the scalp was noted in 120 (96%), arms and legs in 52 (42%), and eyebrows and eyelashes in 47 each (38%),your hair will come back in 3 or 6 months.