Description
Indication & Scope
Medrol® Methylprednisolone Tablets provides adjunctive or maintenance anti-inflammatory treatment for rheumatic diseases, collagen diseases, severe skin disorders, intractable allergies, severe ocular inflammation, respiratory disorders, hematologic diseases, organ transplantation, cerebral edema, multiple sclerosis and endocrine insufficiency; used for symptomatic relief of severe inflammatory and autoimmune conditions.
- Mechanism: Synthetic intermediate-acting glucocorticoid. It binds intracellular glucocorticoid receptors to suppress inflammatory cytokine release, inhibit immune cell proliferation, reduce tissue edema, exudation and scar formation, with weak sodium-retaining mineralocorticoid activity compared with prednisone.
- Drug class: Systemic synthetic glucocorticoid; anti-inflammatory and immunosuppressive prescription agent.
- Clinical use: Short-term acute control of severe inflammation and autoimmune flares; long-term low-dose maintenance for chronic autoimmune diseases; immunosuppression before and after organ transplantation; cerebral edema rescue; multiple sclerosis acute episode treatment; endocrine replacement for adrenal insufficiency.
| Generic Name | Methylprednisolone Tablets |
| Brand Name | Medrol |
| Ingredient | Methylprednisolone |
| Dosage Form | Tablets |
| Package | 4mg*30 tablets/box |
| Conditions Treated | Active rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, severe asthma, severe allergic reactions, pemphigus, transplant rejection prophylaxis, cerebral edema, multiple sclerosis exacerbations, adrenal cortical insufficiency |
| Taboos | Systemic fungal infection; confirmed hypersensitivity to methylprednisolone or tablet excipients; known severe milk protein allergy for certain formulations |
| Place of origin | Localita’ Marino del Tronto, 63100 Ascoli Piceno(AP), Italy |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed, light-proof storage at 15°C – 25°C; keep tightly closed and away from high humidity and heat |
| Manufacturer | Pfizer Italia Srl |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20150245 |
| Approval Date | Jul 23, 2023 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Initial daily dose ranges from 4mg to 48mg for routine cases; high-dose regimens: 200mg daily for multiple sclerosis, 200–1000mg daily for cerebral edema, up to 7mg/kg daily for organ transplantation; long-term use requires gradual dose tapering to the lowest effective maintenance dose.
Time: Can be taken with food to reduce gastric irritation; fixed daily timing for long-term maintenance; alternate-day dosing is applicable for chronic use to lower side effects.
Instructions for use: Never stop medication abruptly after long-term continuous use; gradual dose reduction is mandatory to avoid adrenal crisis; regular monitoring of blood sugar, blood pressure, bone density and gastrointestinal status is required; dosage adjustment is needed during physical stress such as infection or surgery.
Interaction: Combination with NSAIDs increases gastric ulcer risk; barbiturates, rifampicin accelerate hepatic metabolism and reduce efficacy; warfarin anticoagulant effect is altered; hypoglycemic agents require dosage adjustment due to elevated blood glucose; live vaccines are contraindicated during administration.
Side effects:
1. Common: gastric discomfort, elevated blood glucose, insomnia, mood changes, fluid retention, mild hypertension.
2. Severe: gastric ulcer, osteoporosis, adrenal suppression, increased infection susceptibility, hyperglycemia, cataract, glaucoma, avascular necrosis of bone, electrolyte disturbance.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What core pharmacological advantage distinguishesMethylprednisolone Tablets from many other oral glucocorticoids?
It delivers strong anti-inflammatory activity with very weak sodium and water retention effects, reducing edema and hypertension risks.
What mandatory measure must be taken when long-term administration of Methylprednisolone Tablets needs to be discontinued?
Slow gradual dose tapering is required; abrupt stopping triggers adrenal insufficiency crisis and severe disease rebound.
What types of infection completely prohibit the use of Methylprednisolone Tablets?
Systemic whole-body fungal infection is an absolute contraindication for this glucocorticoid preparation.
What common adverse risk rises sharply when Methylprednisolone Tablets is used together with nonsteroidal anti-inflammatory drugs?
Combined use greatly increases the risk of gastric mucosal erosion, gastritis and peptic ulcer formation.
Medrol® | Methylprednisolone Tablets | Anti-inflammatory/Immunosuppressive Diseases | DengYueRX
INN: Methylprednisolone Tablets
Indications: Anti-inflammatory/Immunosuppressive diseases
Dosage Form: Tablets
Strength: 4mg/tablet
Original price was: $6.35.$5.40Current price is: $5.40.
Low MOQ
WHO-GMP
Worldwide Delivery
Compliance and Regulatory Documents
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