sandimmun ciclosporin injection 5ml 250mg 10vials per box

Description

Indication & Scope

Ciclosporin Injection inhibits calcineurin activity and reduces interleukin-2 synthesis in T lymphocytes. It suppresses cell-mediated immunity to avoid solid organ transplant rejection.

Mechanism
Calcineurin inhibitor
Drug class
Injectable systemic immunosuppressant / Anti-rejection concentrate for transplantation
Clinical use
Calcineurin inhibitor immunosuppressant. Inhibits T-lymphocyte activation to suppress cellular immune response and prevent transplant rejection. Only for intravenous use when oral administration is not feasible.

Specification

Generic Name	Ciclosporin Injection
Brand Name	Sandimmun®/Cisen®
Ingredient	Ciclosporin
Dosage Form	Injection
Package	5ml:250mg*10vials/box; 5ml:0.25g/vial
Conditions Treated	Prevention of acute allograft rejection after kidney, liver, heart, lung and pancreas solid organ transplantation; prevention and treatment of graft-versus-host disease following bone marrow transplantation. Reserved for patients unable to receive oral ciclosporin.
Taboos	Hypersensitivity to ciclosporin, polyoxyl 35 castor oil or any excipients of the preparation.
Place of origin	Switzerland; China
Priscription Type	Prescription Drug
Storage Conditions	Sealed, store below 30°C, protected from light
Manufacturer	Novartis Pharma Stein AG; Cisen Pharmaceutical Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA)
Approval number	HJ20150095; H20113117
Approval Date	June 27, 2024; May 09, 2025
Shelf Life	48 months; 24 months

How to use ?

Recommended Dose: Dilute with normal saline or 5% glucose solution before use. Dosage adjusted individually based on monitoring of whole-blood ciclosporin trough concentration.

Time: Intravenous infusion, slowly infused over 2–6 hours.

Instructions for use: Monitor whole blood ciclosporin trough concentration, renal function and blood pressure continuously during treatment. Observe hypersensitivity reactions throughout infusion.

Interaction: Medicines affecting CYP3A4 significantly alter ciclosporin blood concentration; regular trough concentration monitoring is mandatory. Concomitant nephrotoxic medicines increase renal injury risk. Live vaccines are prohibited during treatment.

Side effects: Renal dysfunction, hypertension, hand tremor, hirsutism, dyslipidaemia.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support