Description

Indication & Scope

MEISHILUN® is a prescription carbonic anhydrase inhibitor indicated for reducing elevated intraocular pressure in open-angle glaucoma, secondary glaucoma, and for short-term preoperative treatment of acute angle-closure glaucoma. It is also used for the prevention and treatment of acute mountain sickness and as an adjunctive therapy for certain seizure disorders, edema associated with heart failure or drug therapy, central diabetes insipidus, and hypercalciuria.

Mechanism: Acetazolamide inhibits carbonic anhydrase, reducing aqueous humor production in the eye, promoting renal bicarbonate excretion, inducing mild diuresis, and stimulating ventilation through mild metabolic acidosis.
Drug class: Carbonic anhydrase inhibitor.
Clinical use: Treatment of glaucoma, prevention and treatment of acute mountain sickness, adjunctive therapy for absence seizures and edema, and selected metabolic disorders.

Specification

Generic Name	Acetazolamide Tablets
Brand Name	MEISHILUN®
Ingredient	Acetazolamide
Dosage Form	Tablet
Package	0.25 g/tablet, 6 tablets/box
Conditions Treated	Glaucoma, acute mountain sickness, edema, absence seizures
Taboos	Hypersensitivity to acetazolamide or sulfonamides, severe renal or hepatic impairment, hyponatremia, hypokalemia, hyperchloremic acidosis, adrenal insufficiency
Place of origin	China
Prescription type	Prescription Drug (Rx)
Storage Conditions	Store below 25°C in a dry place, protected from light and moisture.
Manufacturer	Gansu Changee Bio-pharmaceutical Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H62020120
Approval Date	December 25, 2024
Shelf Life	24 months

How to use ?

Recommended Dose: Adults generally take 250–500 mg daily, depending on the indication. Dosage should be individualized by the physician.

Time: Oral administration. May be taken with food to reduce gastrointestinal discomfort.

Instructions for use: Swallow tablets with sufficient water. Maintain adequate hydration and monitor serum electrolytes during prolonged therapy.

Interaction: Avoid concomitant use with high-dose aspirin. Monitor when used with lithium, digoxin, anticonvulsants, or other diuretics.

Side effects: Common adverse reactions include paresthesia, increased urination, fatigue, dizziness, nausea, taste alteration, electrolyte imbalance, metabolic acidosis, and skin rash. Rare but serious reactions include severe hypersensitivity, blood dyscrasias, and kidney stones.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What is MEISHILUN® used for?

It is primarily used to lower intraocular pressure in glaucoma and to prevent or treat acute mountain sickness.

Can it be used before climbing to high altitude?

Yes. Acetazolamide is commonly started 24–48 hours before ascent and continued during exposure to high altitude as directed by a physician.

Can Acetazolamide be taken long-term?

Long-term treatment may require regular monitoring of electrolytes, kidney function, and acid-base balance due to the risk of metabolic disturbances.

Who should not use Acetazolamide?

Patients with sulfonamide allergy, severe kidney or liver disease, adrenal insufficiency, significant electrolyte abnormalities, or hyperchloremic metabolic acidosis should not use this medicine.