Description
Indication & Scope
Etoposide Soft Capsules (Lastet®) is podophyllotoxin derivative and topoisomerase II inhibitor, cell-cycle specific agent acting on S and G2 phase. It stabilizes topoisomerase II-DNA complex, blocks DNA double-strand repair, causes irreversible DNA damage and induces tumor cell apoptosis. Oral capsule achieves sustained blood concentration for long-cycle anti-tumor therapy.
- Mechanism
Inhibit topoisomerase II, block DNA repair, arrest cell cycle at G2 phase - Drug class
Topoisomerase II inhibitor cytotoxic chemotherapeutic agent / Podophyllotoxin derivative - Clinical use
SCLC, malignant lymphoma
| Generic Name | Etoposide Soft Capsules |
| Brand Name | Lastet® |
| Ingredient | Etoposide |
| Dosage Form | Soft Capsules |
| Package | 25mg*40 capsules/box |
| Conditions Treated | Small cell lung cancer (SCLC); Malignant lymphoma |
| Taboos | Severe myelosuppression; severe hypersensitivity to etoposide; pregnant and lactating women |
| Place of origin | Fujinomiya, Shizuoka Prefecture, Japan |
| Priscription Type | Prescription drug (Rx) |
| Storage Conditions | Store at 2℃-8℃, protected from light, sealed |
| Manufacturer | Shibakawa Plant, Fuji Capsule Co.,Ltd. |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | H10940003 |
| Date of Revision | July 29, 2025 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: 175–200mg daily for adults, continuous oral administration for 5 days, repeat cycle every 3 weeks; adjust dosage for liver/renal dysfunction patients
Time: Oral administration, long-term continuous dosing improves anti-tumor activity; periodic blood routine monitoring required
Interaction: Avoid concurrent myelosuppressive agents, additive hematologic toxicity will occur
Side effects: Leukopenia, thrombocytopenia, nausea and vomiting, alopecia, hepatic function abnormality
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is the core molecular target of etoposide soft capsules?
Topoisomerase II.
What is the main dose-limiting adverse reaction of this drug?
Myelosuppression (leukopenia, thrombocytopenia).
What is the main excretion pathway of etoposide?
Renal excretion.
What routine test must be reviewed regularly during oral treatment?
Peripheral blood routine test.
Lastet® | Etoposide Soft Capsules | SCLC and Malignant Lymphoma | DengYueRX
INN: Etoposide
Indications: SCLC (Small cell lung cancer ) and Malignant Lymphoma
Dosage Form: Soft Capsules
Strength: 25mg/Capsule
Original price was: $415.97.$353.57Current price is: $353.57.
