glurenorm gliquidone tablet 30mg per tablet 60tablets per carton

Description

Indication & Scope

Glurenorm® is a prescription second-generation sulfonylurea indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It stimulates pancreatic β-cells to increase insulin secretion and is particularly suitable for patients with mild renal impairment because the drug is predominantly eliminated via the biliary tract.

Mechanism: Gliquidone stimulates insulin release by binding to sulfonylurea receptors (SUR1) on pancreatic β-cells, leading to closure of ATP-sensitive potassium channels, membrane depolarization, calcium influx, and insulin secretion.
Drug class: Second-generation sulfonylurea.
Clinical use: Treatment of adults with type 2 diabetes mellitus inadequately controlled by diet and exercise alone, especially patients with mild renal impairment. Not indicated for type 1 diabetes, diabetic ketoacidosis, or diabetic coma.

Specification

Generic Name	Gliquidone Tablets
Brand Name	Glurenorm®
Ingredient	Gliquidone
Dosage Form	Tablet
Package	30 mg/tablet, 60 tablets/carton
Conditions Treated	Glycemic control in adults with type 2 diabetes mellitus
Taboos	Hypersensitivity to gliquidone or sulfonylureas; type 1 diabetes; diabetic ketoacidosis; diabetic coma or pre-coma; severe renal failure
Place of origin	China
Prescription type	Prescription Drug (Rx)
Storage Conditions	Store in a tightly closed container at room temperature, protected from light and moisture.
Manufacturer	Beijing Wanhui Double‑Crane Pharmaceutical Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H10940258
Approval Date	May 28, 2025
Shelf Life	70 months

How to use ?

Recommended Dose: The usual starting dose is 15–30 mg daily before breakfast. The dosage should be individualized according to blood glucose control. Daily doses above 30 mg should be divided before meals. The maximum recommended daily dose is 180 mg.

Time: Take approximately 30 minutes before meals.

Instructions for use: Swallow the tablet with water before meals. The tablet may be divided if necessary. Continue dietary management and regular exercise throughout treatment. Regular blood glucose monitoring is recommended, particularly in elderly patients and those at risk of hypoglycemia.

Interaction: The glucose-lowering effect may be enhanced by insulin, metformin, DPP-4 inhibitors, SGLT2 inhibitors, salicylates, and β-blockers, while corticosteroids, thiazide diuretics, oral contraceptives, and thyroid hormones may reduce its efficacy. β-blockers may also mask symptoms of hypoglycemia.

Side effects: Common adverse reactions include hypoglycemia, dizziness, sweating, tremor, gastrointestinal discomfort, nausea, abdominal fullness, skin rash, pruritus, and headache. Rare adverse reactions include hepatic dysfunction, thrombocytopenia, leukopenia, and allergic reactions.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What is Glurenorm® used for?

It is used to improve blood glucose control in adults with type 2 diabetes mellitus when diet and exercise alone are insufficient.

Is Glurenorm® suitable for patients with kidney impairment?

Yes. Because most gliquidone is eliminated through the biliary system and only a small amount is excreted by the kidneys, it is considered a suitable sulfonylurea for patients with mild to moderate renal impairment. It should not be used in severe renal failure.

When should Glurenorm® be taken?

It should be taken about 30 minutes before meals.

Can Glurenorm® cause hypoglycemia?

Yes. Hypoglycemia is the most common adverse reaction, especially when meals are skipped, alcohol is consumed, or the medicine is combined with other glucose-lowering agents.