Description
Indication & Scope
BIO THREE TABLETS® (Clostridium butyricum TO-A; Bacillus subtilis TO-A; Enterococcus faecium T-110) is a prescription probiotic preparation containing three live bacterial strains, indicated to improve symptoms associated with intestinal flora imbalance, including diarrhea, constipation, alternating diarrhea and constipation, and enteritis.
- Mechanism: The three bacterial strains coexist and proliferate in the intestinal tract, helping restore intestinal microbial balance and inhibit the growth of potentially harmful bacteria.
- Drug class: Live bacterial preparation / intestinal flora regulator.
- Clinical use: Symptomatic management of intestinal flora imbalance, including diarrhea, constipation, alternating diarrhea and constipation, and enteritis.
| Generic Name | Clostridium butyricum TO-A; Bacillus subtilis TO-A; Enterococcus faecium T-110 |
| Brand Name | BIO THREE TABLETS® |
| Ingredient | Clostridium butyricum TO-A; Bacillus subtilis TO-A; Enterococcus faecium T-110 |
| Dosage Form | Tablet |
| Package | 200 mg/tablet, 12 tablets/box |
| Conditions Treated | Intestinal flora imbalance, including diarrhea, constipation and enteritis |
| Taboos | Hypersensitivity to this product or its components; milk allergy |
| Place of origin | Japan |
| Prescription type | Prescription Drug (Rx) |
| Storage Conditions | Store sealed in a cool, dry place; avoid high temperatures |
| Manufacturer | TOA BIOPHARMA CO., LTD. Tatebayashi Plant |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval Number | SJ20160008 |
| Approval Date | May 20, 2026 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Adults: 2 tablets three times daily. Children 5–15 years: Half the adult dose. Children 3 months–5 years: Use under medical guidance; disperse in warm water before administration.
Time: 3 times daily.
Instructions for use: Take orally. Do not use hot water, as the product contains live bacteria.
Interaction: Do not mix directly with aminophylline or isoniazid, as discoloration may occur.
Side effects: No definite adverse reactions were reported in the available 355-case clinical study; allergic reactions such as rash or itching may occur.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is BIO THREE TABLETS® used for?
It is used to improve symptoms caused by intestinal flora imbalance, including diarrhea, constipation, alternating diarrhea and constipation, and enteritis.
Can children take BIO THREE TABLETS®?
Yes. Children 5–15 years generally use half the adult dose; children 3 months–5 years should use it under medical guidance.
Can BIO THREE TABLETS® be taken with hot water?
No. Because it contains live bacterial preparations, use warm water rather than hot water.
Who should not use BIO THREE TABLETS®?
Patients with a history of hypersensitivity to the product or its components, and patients with milk allergy, should not use it.
BIO THREE TABLETS® | Clostridium butyricum TO-A; Bacillus subtilis TO-A; Enterococcus faecium T-110 | Diarrhea and Constipation | DengYueRX
INN: Clostridium butyricum TO-A; Bacillus subtilis TO-A; Enterococcus faecium T-110
Indications: Intestinal flora imbalance
Dosage Form: Tablet
Strength: 200 mg/Tablet
Original price was: $6.25.$5.31Current price is: $5.31.
