Description
Indication & Scope
WuDuLi® is a prescription potassium-sparing diuretic combination indicated for the treatment of hypertension and edema associated with congestive heart failure, hepatic cirrhosis, and other conditions involving fluid retention.
- Mechanism: Amiloride blocks epithelial sodium channels (ENaC) in the distal nephron to reduce potassium loss, while hydrochlorothiazide inhibits sodium and chloride reabsorption in the distal convoluted tubule to enhance natriuresis and diuresis.
- Drug class: Potassium-sparing diuretic / thiazide diuretic combination.
- Clinical use: Treatment of hypertension and edema associated with heart failure, hepatic cirrhosis, and fluid retention disorders while reducing the risk of thiazide-induced hypokalemia.
| Generic Name | Compound Amiloride Hydrochloride Tablets |
| Brand Name | WuDuLi® |
| Ingredient | Amiloride Hydrochloride + Hydrochlorothiazide |
| Dosage Form | Tablet |
| Package | 100 tablets/bottle |
| Conditions Treated | Hypertension; edema and ascites associated with congestive heart failure and hepatic cirrhosis |
| Taboos | Hyperkalemia, anuria, severe renal impairment, hypersensitivity to amiloride, hydrochlorothiazide, or sulfonamide-derived drugs |
| Place of origin | China |
| Prescription type | Prescription Drug (Rx) |
| Storage Conditions | Store in a tightly closed container at room temperature, protected from light and moisture. |
| Manufacturer | Jiangsu Desano Pharmaceutical Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval Number | H10900029 |
| Approval Date | July 25, 2025 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: 1–2 tablets orally once daily. In patients with severe edema, the dose may be divided into twice-daily administration according to clinical response.
Time: Take after meals, preferably in the morning.
Instructions for use: Swallow tablets with water. Monitor serum potassium, sodium, renal function, blood pressure, and uric acid regularly. Avoid potassium supplements or other potassium-sparing diuretics unless directed by a physician.
Interaction: Use caution with ACE inhibitors, ARBs, potassium supplements, spironolactone, eplerenone, digoxin, lithium, NSAIDs, and corticosteroids.
Side effects: Common adverse reactions include nausea, dry mouth, dizziness, fatigue, hyperkalemia, hyponatremia, hyperuricemia, orthostatic hypotension, and skin rash.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is WuDuLi® (Compound Amiloride Hydrochloride Tablets) used for?
WuDuLi® (Compound Amiloride Hydrochloride Tablets) is used to treat hypertension and edema associated with congestive heart failure, hepatic cirrhosis, and other fluid retention disorders.
Why does WuDuLi® (Compound Amiloride Hydrochloride Tablets) contain two diuretics?
Hydrochlorothiazide increases sodium and water excretion, while amiloride helps prevent excessive potassium loss caused by thiazide therapy.
Can I take potassium supplements while using WuDuLi® (Compound Amiloride Hydrochloride Tablets)?
Generally, no. Potassium supplements or other potassium-sparing diuretics may increase the risk of hyperkalemia unless prescribed by a physician.
What should be monitored during treatment?
Serum potassium, sodium, renal function, blood pressure, and uric acid should be monitored regularly.
WuDuLi® | Compound Amiloride Hydrochloride | Edema | DengYueRX
INN: Compound Amiloride Hydrochloride
Indications: Edema
Dosage Form: Tablet
Strength: Amiloride Hydrochloride 2.5 mg + Hydrochlorothiazide 25 mg/Tablet
Original price was: $4.24.$3.60Current price is: $3.60.
