Description
Indication & Scope
Docetaxel Injection (DuoPaFei®)is a taxane anti-mitotic chemotherapeutic agent. It promotes microtubule assembly and inhibits microtubule depolymerization, blocking cancer cell mitosis and inducing tumor cell death.
- Mechanism
Stabilize microtubule structure, inhibit microtubule disassembly, arrest tumor cell division, induce apoptosis - Drug class
Taxane Chemotherapeutic / Cytotoxic Antineoplastic Drug - Clinical use
Treatment of locally advanced and metastatic breast cancer and non-small cell lung cancer
| Generic Name | Docetaxel Injection |
| Brand Name | DuoPaFei® |
| Ingredient | Docetaxel |
| Dosage Form | Injection |
| Package | 40ml/vial |
| Conditions Treated | Locally advanced or metastatic breast cancer;Locally advanced or metastatic non-small cell lung cancer (including disease progressing after platinum-based chemotherapy) |
| Taboos | Hypersensitivity to docetaxel, polysorbate 80 or other excipients |
| Place of origin | Shandong,China |
| Priscription Type | Prescription drug (Rx) |
| Storage Conditions | Store at 2℃-8℃, protected from light, sealed |
| Manufacturer | Qilu Pharmaceutical Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | H20041128 |
| Date of Revision | June 21, 2021 |
| Shelf Life | 18 months |
How to use ?
Recommended Dose: 75mg/m², intravenous infusion over 1 hour, once every 3 weeks; premedicate with oral dexamethasone (16mg daily for at least 3 days) to prevent hypersensitivity and fluid retention
Time: Intravenous slow drip over 1 hour, only for intravenous infusion, not bolus injection
Interaction: Enhanced myelosuppression with other chemotherapeutic agents; caution with CYP3A4 inhibitors; dose adjustment required for liver dysfunction
Side effects: Neutropenia, hypersensitivity reactions, fluid retention, skin/nail disorders, fatigue, mucositis, gastrointestinal discomfort, peripheral neuropathy
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
Why is liver function monitoring important?
Docetaxel is mainly metabolized by the liver; severe liver dysfunction increases toxic risk and requires dose reduction.
What premedication is required before administration?
Oral dexamethasone, 16mg daily for at least 3 days, to prevent allergic reactions and fluid retention.
Can it be given by rapid intravenous bolus?
No, it must be administered as a 1-hour slow intravenous infusion.
What should be done for severe hypersensitivity reactions?
Immediately stop infusion, give emergency treatment, and do not reuse docetaxel afterwards.
DuoPaFei® | Docetaxel Injection | Breast Cancer and NSCLC | DengYueRX
INN: Docetaxel
Indications: Breast Cancer and NSCLC (non-small cell lung cancer )
Dosage Form: Injection
Strength: 40ml/Vial
Original price was: $11.48.$9.76Current price is: $9.76.
