YunKun® (Danzhi Xiaoyao Pills) is a traditional Chinese medicine preparation used to soothe the liver, relieve stagnation, clear heat, and regulate menstruation. They are indicated for liver-Qi stagnation transforming into heat, characterized by chest and hypochondriac distension or pain, irritability, dry mouth, poor appetite, hot flashes, and menstrual disorders such as early menstruation, difficult menstrual flow, breast distension, and lower abdominal pain.

• Mechanism: Bupleurum Root is traditionally used to soothe the liver and regulate qi; Angelica Root and Paeonia Root nourish the blood and regulate the liver; Gardenia Fruit and Moutan Bark help clear heat; Poria and Atractylodes Rhizome support the spleen. The combined formulation is traditionally used to soothe the liver, clear heat, regulate qi and blood, and relieve associated symptoms.
• Drug class: Traditional Chinese medicine; liver-soothing, heat-clearing, and menstruation-regulating preparation.
• Clinical use: Symptomatic management of liver-Qi stagnation with heat, including irritability, chest and hypochondriac discomfort, dry mouth, poor appetite, hot flashes, and associated menstrual discomfort.