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jingxin dimdazenil capsule 2

Description

 Indication & Scope

Short-term treatment of insomnia disorder in adult patients.

  • Mechanism: Didadexin selectively partially activates GABAₐ receptors containing α2/α3 subunits.
  • Drug class: Novel partial positive allosteric modulator of GABAₐ receptors; new-generation benzodiazepine sedative-hypnotic drug; Class II psychotropic prescription medicine.
  • Clinical use:1. First-line short-term hypnotic for adults with difficulty falling asleep, frequent nighttime awakenings or insufficient total sleep time.2. Suitable for patients who cannot tolerate side effects of traditional benzodiazepines and z-drugs.3. Restricted to short-term administration; the treatment cycle shall not exceed 4 weeks under physician supervision.4. Administered orally before bedtime on an empty stomach; dosage is adjusted by psychiatrists or sleep specialists according to individual sleep conditions.
Specification
Generic Name Dimdazenil Capsules
Brand Name Jingxin
Ingredient Dimdazenil Capsules
Dosage Form Capsules
Package 2.5mg*7 capsules/box
Conditions Treated Short-term treatment of insomnia disorder in adult patients.
Taboos 1. Patients with hypersensitivity to dimdazenil or any excipients of the capsule

2. Patients with myasthenia gravis

3. Patients with severe sleep apnea syndrome

4. Patients with severe respiratory insufficiency

5. Those who have experienced complex sleep-related behaviors after taking this drug before

Place of origin China
Prescription type Prescription-only
Storage Conditions
Manufacturer Jingxin PharmaceuticalCo., Ltd
Registration Authority National Medical Products Administration (NMPA), China
Approval number H20230030
Date of Revision 2023
Shelf Life 24 months

How to use ?

Recommended Dose: The standard starting dose for adults is 2.5 mg taken orally once daily. Dose adjustment is allowed under specialist supervision based on individual sleep response and tolerance, and the maximum daily dose should not exceed 2.5 mg.

 

Time: Take the capsule on an empty stomach immediately before bedtime. Avoid administration with food or within 2 hours after meals, as food will delay its onset of action. The total treatment course should not exceed 4 weeks.

 

Instructions for use:

1. Swallow the hard capsule whole with plain water; do not crush, split or chew the contents.

2. Only use it for short-term management of insomnia as prescribed by psychiatrists or sleep physicians.

3. Gradually taper the dose when discontinuing treatment to avoid rebound insomnia; abrupt cessation is prohibited.

4. Avoid operating machinery, driving or performing concentration-demanding tasks after intake due to sedative effects.

 

Interaction:

1. Strong CYP3A4 inhibitors/inducers may alter blood drug concentration, so co-administration needs strict medical monitoring.

2. Combined use with opioids, other sedatives or central depressants will raise risks of deep sedation, respiratory suppression and even coma, which is contraindicated in most cases.

3. It has low interaction risks with common antihypertensives, antidepressants and hypoglycemic agents, but clinical evaluation is still required before combined medication.

4. Alcohol will amplify its central inhibitory effect, alcoholic drinks are forbidden during the whole treatment period.

 

Side effects:

1. Common: Mild drowsiness, headache, dry mouth, nausea, fatigue.
2. Uncommon: Dizziness, nightmares, slight gait unsteadiness.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References
2.NMPA
3.FDA
4.EMA

FAQ

What disease can Dimdazenil treat?

Short-term treatment of insomnia disorder in adults.

How does Dimdazenil differ from traditional benzodiazepines?

It is a partial positive allosteric modulator of GABAₐ receptors with milder central inhibition, lower risks of drug dependence and daytime drowsiness.

What is the maximum treatment course of this dimdazenil?

The total treatment duration shall not exceed 4 weeks under doctors’ supervision.

Who are forbidden to take Dimdazenil?

Patients with drug hypersensitivity, myasthenia gravis, severe sleep apnea or severe respiratory insufficiency.

JingXin® | Dimdazenil Capsules | Insomnia | DengYueRX

INN: Dimdazenil Capsules
Indications: Short-term treatment of insomnia disorder in adult patients.
Dosage Form: Capsules
Strength: 2.5mg/capsule

Low MOQ

WHO-GMP

Worldwide Delivery

Compliance and Regulatory Documents

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