Description
Indication & Scope
Doxofylline Injection relieve dyspnea caused by bronchospasm from bronchial asthma, chronic asthmatic bronchitis and other airway spasm disorders.
- Mechanism: A methylxanthine derivative that inhibits intracellular phosphodiesterase to raise cAMP levels, directly relaxing bronchial smooth muscle, reducing airway spasm and mild airway inflammation. It has weaker central excitation than theophylline.
- Drug class: Methylxanthine bronchodilator, anti-asthmatic agent.
- Clinical use: Short-term intravenous treatment for moderate dyspnea from bronchospasm when oral or inhaled medicines fail to control symptoms.
| Generic Name | Doxofylline Injection |
| Brand Name | – |
| Ingredient | Doxofylline |
| Dosage Form | Injection |
| Package | 10ml: 0.1g (quantity to be determined) |
| Conditions Treated | Bronchial asthma, chronic asthmatic bronchitis, dyspnea from reversible bronchoconstriction |
| Taboos | Hypersensitivity to doxofylline or any xanthine derivatives; acute myocardial infarction; lactation period |
| Place of origin | China |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed storage at controlled room temperature (10°C–30°C), protected from strong light and freezing |
| Manufacturer | Shandong Hualu Pharmaceutical Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20223865 |
| Approval Date | Nov 22, 2022 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: 200mg for slow IV injection every 12 hours after dilution; 300mg once daily for IV infusion; course lasts 5–10 days.
Time: IV injection at 12-hour intervals; IV infusion once daily at a fixed time.
Instructions for use: Dilute with glucose injection before IV injection, inject slowly over more than 20 minutes; infuse slowly over 45+ minutes; monitor blood drug concentration during long courses.
Interaction: Forbidden to combine with other xanthine drugs; caution with ephedrine and sympathomimetic agents; avoid heavy caffeine intake.
Side effects:
1. Common: nausea, abdominal discomfort, headache, insomnia, mild tachycardia.
2. Severe overdose: arrhythmia, convulsions, high blood sugar.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What kinds of respiratory symptoms are suitable for intravenous Doxofylline Injection?
Dyspnea triggered by bronchospasm in asthma and chronic asthmatic bronchitis.
What three groups are completely prohibited from using Doxofylline Injection?
People allergic to xanthines, patients with acute myocardial infarction, and lactating women cannot use it.
What speed requirement applies to intravenous injection and infusion when using Doxofylline Injection?
IV injection takes over 20 minutes; IV infusion must last more than 45 minutes to avoid toxicity.
What monitoring measure is needed for a full treatment course of Doxofylline Injection?
Regular blood concentration monitoring is required to stay within the safe therapeutic range.
Doxofylline Injection | Bronchial Asthma/COPD | DengYueRX
INN: Doxofylline Injection
Indications: Bronchial Asthma, COPD
Dosage Form: Injection
Strength: 10ml: 0.1g/vial
Original price was: $0.36.$0.31Current price is: $0.31.
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