Description
Indication & Scope
symptomatic improvement treatment for mild and moderate Alzheimer’s disease.
- Mechanism: Reversibly inhibits acetylcholinesterase, increases acetylcholine concentration in brain tissue, improves central cholinergic nerve conduction, and relieves cognitive and memory dysfunction of Alzheimer’s disease.
- Drug class: Central acetylcholinesterase inhibitor, anti-dementia therapeutic agent.
- Clinical use: Long-term symptomatic maintenance treatment for patients with mild and moderate Alzheimer’s disease.
| Generic Name | Donepezil Hydrochloride Tablets |
| Brand Name | YiZhi |
| Ingredient | Donepezil Hydrochloride |
| Dosage Form | Tablets |
| Package | 5mg (calculated by C₂₄H₂₉NO₃·HCl)*7 tablets/box;
5mg (calculated by C₂₄H₂₉NO₃·HCl)*28 tablets/box; 10mg (calculated by C₂₄H₂₉NO₃·HCl)*7 tablets/box |
| Conditions Treated | Mild and moderate Alzheimer’s disease |
| Taboos | Hypersensitivity to donepezil hydrochloride or tablet excipients; severe bradycardia and atrioventricular block |
| Place of origin | China |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed storage at room temperature, protect from strong light and humid environment |
| Manufacturer | Zhejiang Huahai Pharmaceutical Co.,Ltd.; Zhejiang Huahai Pharmaceutical Technology Co.,Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20183417; H20183418 |
| Approval Date | Apr 28, 2023 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: 5mg once daily for initial treatment, can be increased to 10mg once daily after one month of stable medication.
Time: Once daily, bedtime administration before sleep.
Instructions for use: Swallow whole with water, take continuously, dosage adjustment requires gradual titration under medical guidance.
Interaction: Anticholinergic drugs antagonize therapeutic effects; cholinergic drugs enhance drug efficacy and adverse reactions.
Side effects:
1. Common: mild nausea, vomiting, insomnia, muscle spasm, dizziness.
2. Rare: bradycardia, gastrointestinal bleeding, fatigue.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What stage of Alzheimer’s disease is suitable for Donepezil Hydrochloride Tablets treatment?
It is only applicable for symptomatic improvement of mild and moderate Alzheimer’s disease.
What core brain function does Donepezil Hydrochloride Tablets improve through its pharmacological mechanism?
It improves central nerve conduction to alleviate memory and cognitive dysfunction caused by dementia.
What cardiac conduction problems forbid the use of Donepezil Hydrochloride Tablets?
Severe bradycardia and atrioventricular block are absolute contraindications.
What is the standard administration time for daily medication of Donepezil Hydrochloride Tablets?
Fixed bedtime administration before sleep is the recommended routine dosing time.
YiZhi® | Donepezil Hydrochloride Tablets | Alzheimer’s Disease | DengYueRX
INN: Donepezil Hydrochloride Tablets
Indications: Alzheimer’s disease
Dosage Form: Tablets
Strength: 5mg (calculated by C₂₄H₂₉NO₃·HCl)/tablet
Original price was: $5.85.$4.97Current price is: $4.97.
