Description
Indication & Scope
Zorifertinib Hydrochloride Tablets provides targeted treatment for adult patients with locally advanced or metastatic non-small cell lung cancer.
- Mechanism: Selective EGFR tyrosine kinase inhibitor blocks EGFR intracellular signaling pathway, inhibits proliferation of EGFR-mutated lung cancer cells.
- Drug class: EGFR-TKI targeted anti-tumor small molecule drug.
- Clinical use: First-line targeted therapy for EGFR-mutant advanced non-small cell lung cancer.
| Generic Name | Zorifertinib Hydrochloride Tablets |
| Brand Name | ZeRuiNi |
| Ingredient | Zorifertinib Hydrochloride Tablets |
| Dosage Form | Tablets |
| Package | 100mg*28 tablets/box |
| Conditions Treated | Locally advanced or metastatic non-small cell lung cancer |
| Taboos | 1. Known severe hypersensitivity to zorifertinib hydrochloride or tablet auxiliary materials
2. Patients with active interstitial lung disease 3. Pregnant women without clinical benefit-risk assessment |
| Place of origin | China |
| Prescription type | Prescription-only |
| Storage Conditions | Sealed storage at 15°C ~ 30°C, avoid high temperature and high humidity |
| Manufacturer | ChenTai Pharmaceutical Technology, Ltd |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20240038; H20240039 |
| Approval Date | Nov 15, 2024 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Fixed oral dose once daily.
Time: Taken at a consistent fixed time every day.
Instructions for use: Swallow the whole tablet with water, food intake does not affect absorption.
Interaction: Strong CYP3A4 inducers and inhibitors will affect blood drug concentration, avoid combined use without medical guidance.
Side effects: Skin rash, diarrhea, xerosis cutis, stomatitis, paronychia, fatigue.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is the treatment scope of Zorifertinib Hydrochloride Tablets?
It is used for targeted treatment of locally advanced or metastatic non-small cell lung cancer in adult patients.
Which patients are contraindicated for Zorifertinib Hydrochloride Tablets this targeted drug?
Patients with severe drug hypersensitivity and active interstitial lung disease are prohibited from medication.
What are the typical adverse reactions of Zorifertinib Hydrochloride Tablets?
Common side effects include skin rash, diarrhea, dry skin, stomatitis, paronychia and physical fatigue.
What is the pharmacological mechanism of Zorifertinib Hydrochloride Tablets?
It acts as an EGFR tyrosine kinase inhibitor to block EGFR signaling and inhibit mutant lung cancer cell proliferation.
ZeRuiNi® | Zorifertinib Hydrochloride Tablets | Lung Cancer | DengYueRX
INN: Zorifertinib Hydrochloride Tablets
Indications: Lung Cancer
Dosage Form: Tablets
Strength: 100mg/tablet; 50mg/tablet
