Description
Indication & Scope
Apatinib Mesylate Tablets (AiTan®) is an oral small-molecule tyrosine kinase inhibitor that selectively inhibits VEGFR-2, blocking VEGF-mediated tumor angiogenesis, cutting off tumor blood supply and inhibiting tumor growth and metastasis.
- Mechanism
Inhibit VEGFR-2 tyrosine kinase activity, block tumor angiogenesis, reduce tumor blood supply, suppress tumor progression - Drug class
Oral anti-angiogenic targeted drug / Tyrosine kinase inhibitor - Clinical use
Advanced gastric cancer, gastroesophageal junction adenocarcinoma, advanced hepatocellular carcinoma and other malignant tumors
| Generic Name | Apatinib Mesylate Tablets |
| Brand Name | AiTan® |
| Ingredient | Apatinib Mesylate |
| Dosage Form | Film-coated Tablets |
| Package | 0.375g*10 tablets/box |
| Conditions Treated | Monotherapy for advanced gastric/gastroesophageal junction adenocarcinoma progressing after ≥2 lines of chemotherapy;Monotherapy for advanced hepatocellular carcinoma intolerant to/failing prior ≥1 line systemic treatment;First-line treatment of unresectable/metastatic hepatocellular carcinoma with camrelizumab;gBRCAm HER2-negative metastatic breast cancer treated with fluzoparib |
| Taboos | Hypersensitivity to apatinib or any excipients; severe liver dysfunction; active bleeding, gastrointestinal ulcer, perforation or obstruction; pregnant and lactating women |
| Place of origin | Jiangsu,China |
| Priscription Type | Prescription drug (Rx) |
| Storage Conditions | Store below 30°C, keep in original packaging |
| Manufacturer | Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | H20140104 |
| Date of Revision | December 1, 2024 |
| Shelf Life | 48 months |
How to use ?
Recommended Dose: Advanced gastric cancer: 850mg once daily; single-agent advanced HCC:750mg once daily; adjust dose according to adverse reactions; take orally, do not chew or break
Time: Take 30 minutes after meals with warm water, fixed time daily, do not double dose if missed
Interaction: Caution with CYP3A4 inhibitors/inducers; monitor for bleeding risk with anticoagulants; avoid major surgery within 30 days
Side effects: Hypertension, proteinuria, hand-foot syndrome, bleeding, myelosuppression, diarrhea, liver function abnormalities, QT interval prolongation
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is the core mechanism of apatinib?
It inhibits VEGFR-2, blocks tumor angiogenesis and cuts off the nutrient supply of tumor cells.
Why avoid major surgery within 30 days before taking Apatinib Mesylate Tablets?
Apatinib increases bleeding risk and impairs wound healing.
What is the standard dose for advanced gastric cancer?
850mg once daily, taken continuously until disease progression or intolerable toxicity.
Can children routinely take apatinib?
Not recommended for children, safety and efficacy have not been established.
AiTan® | Apatinib Mesylate Tablets | Breast Cancer,Hepatocellular Carcinoma and Gastric Adenocarcinoma | DengYueRX
INN: Apatinib Mesylate
Indications: Breast Cancer,Hepatocellular Carcinoma and Gastric Adenocarcinoma
Dosage Form: Film-coated Tablets
Strength: 0.375g/Tablet
Original price was: $320.34.$272.29Current price is: $272.29.
