Description
Indication & Scope
Dymista® Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray treats moderate to severe allergic rhinitis, including nasal congestion, rhinorrhea, sneezing and nasal pruritus.
- Mechanism: Azelastine acts as a second-generation antihistamine to block histamine receptors and relieve acute allergic reactions; fluticasone propionate is a topical corticosteroid that inhibits inflammatory cytokine release to reduce chronic nasal inflammation. The two ingredients work synergistically to relieve both acute and persistent allergic symptoms.
- Drug class: Combination of intranasal antihistamine and inhaled corticosteroid.
- Clinical use: Daily maintenance treatment for seasonal and perennial allergic rhinitis.
| Generic Name | Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray |
| Brand Name | Dymista |
| Ingredient | Azelastine Hydrochloride and Fluticasone Propionate |
| Dosage Form | Nasal Spray |
| Package | azelastine hydrochloride 137μg + fluticasone propionate 50μg* 120 sprays/bottle |
| Conditions Treated | Seasonal allergic rhinitis, perennial allergic rhinitis with combined congestion and itching symptoms |
| Taboos | Hypersensitivity to azelastine, fluticasone or any excipients of the formulation |
| Place of origin | Plot No.9&10, Indore Special Economic Zone, Phase II, Pithampur, District Dhar Madhya Pradesh, 454775 Indore, India |
| Prescription type | Prescription-only |
| Storage Conditions | Store at controlled room temperature between 15°C and 30°C, avoid direct sunlight and freezing, keep the bottle tightly sealed |
| Manufacturer | Cipla Limited |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20230090 |
| Approval Date | Jun 30, 2023 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: One spray per nostril twice daily for adults and adolescents over 12 years old.
Time: Morning and evening, at fixed intervals every day.
Instructions for use: Shake well before each use; clear nasal passages first; insert the nozzle into one nostril while blocking the other nostril, spray gently, avoid spraying directly onto the nasal septum.
Interaction: Sedatives and alcohol may enhance mild drowsiness caused by azelastine; strong CYP3A4 inhibitors slightly increase systemic fluticasone absorption.
Side effects:
1. Common: mild nasal dryness, bitter taste, transient headache, slight drowsiness.
2. Rare: nasal septum irritation, epistaxis, throat discomfort.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What kind of rhinitis symptoms are suitable for Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray?
It applies to both seasonal and perennial allergic rhinitis with congestion, runny nose, sneezing and nasal itching.
What is the core advantage of combining two active ingredients in one spray (Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray)?
The antihistamine relieves acute itching and sneezing quickly, while the steroid reduces persistent inflammation and congestion for long-term relief.
What situation makes Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray prohibited for use?
Use is forbidden when hypersensitivity to either active ingredient or auxiliary materials occurs.
What measure can reduce bitter taste after spraying of Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray?
Avoid tilting the head backward severely after administration to prevent liquid flowing down the throat.
Dymista® | Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray | Allergic Rhinitis | DengYueRX
INN: Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray
Indications: Allergic rhinitis
Dosage Form: Nasal Spray
Strength: azelastine hydrochloride 137μg + fluticasone propionate 50μg/spray
Original price was: $34.03.$28.93Current price is: $28.93.
