Description
Indication & Scope
DongZeAn is a prescription SGLT inhibitor indicated for improving glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise.Olorigliflozin is a novel dual SGLT inhibitor that potently inhibits renal SGLT-2 while moderately inhibiting intestinal SGLT-1, helping improve both fasting and postprandial blood glucose levels.
- Mechanism: Olorigliflozin inhibits renal SGLT-2 to reduce glucose reabsorption and increase urinary glucose excretion. Moderate inhibition of intestinal SGLT-1 decreases intestinal glucose absorption, contributing to improved glycemic control.
- Drug class: Sodium-glucose cotransporter (SGLT) inhibitor.
- Clinical use: Improvement of glycemic control in adults with type 2 diabetes mellitus as monotherapy or in combination with metformin.
| Generic Name | Olorigliflozin Capsules |
| Brand Name | DongZeAn® |
| Ingredient | Olorigliflozin |
| Dosage Form | Capsule |
| Package | 20 mg/10 capsules per box |
| Conditions Treated | Type 2 diabetes mellitus |
| Taboos | Hypersensitivity to Olorigliflozin or any component of the product; type 1 diabetes mellitus; diabetic ketoacidosis; end-stage renal disease |
| Place of origin | China |
| Prescription type | Prescription Drug (Rx) |
| Storage Conditions | Store at 2°C–8°C. Do not freeze. |
| Manufacturer | YiChang HEC ChangJiang Pharmaceutical Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | H20260004 |
| Date of Revision | 2026 |
| Shelf Life | Refer to the approved package labeling. |
How to use ?
Recommended Dose: 20 mg administered orally twice daily according to the approved prescribing information.
Time: Take once daily, preferably before breakfast.
Instructions for use: Swallow the capsule whole with water. It may be taken with or without food. Dose adjustment is not required in patients with mild renal impairment (eGFR 60–89 mL/min/1.73 m²). Use is not recommended in patients with eGFR below 60 mL/min/1.73 m².
Interaction: Olorigliflozin is not metabolized by CYP450 enzymes. Concomitant use with diuretics may increase the risk of dehydration.
Side effects: Common adverse reactions include genital and urinary tract infections, increased urination, and dry mouth. Nausea, fatigue, dehydration, and diabetic ketoacidosis may occur.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What is DongZeAn® used for?
It is indicated for improving glycemic control in adults with type 2 diabetes mellitus as monotherapy or in combination with metformin.
How does Olorigliflozin work?
It inhibits SGLT-2 in the kidneys and moderately inhibits SGLT-1 in the intestine, reducing glucose reabsorption and increasing urinary glucose excretion.
Can DongZeAn® be used in patients with type 1 diabetes?
No. DongZeAn® is contraindicated in patients with type 1 diabetes mellitus.
What are the most common side effects?
The most common adverse reactions include urinary tract infections, genital infections, increased urination, and dry mouth.
DongZeAn® | Olorigliflozin | Type 2 Diabetes | DengYueRX
INN: Olorigliflozin
Indications: Type 2 diabetes mellitus
Dosage Form: Capsule
Strength: 20 mg/Capsule
