Description
Indication & Scope
Differin®/MingKangXin® Adapalene Gel is used for the treatment of acne vulgaris, improves skin symptoms such as comedones, papules and pustules, and regulates skin keratin metabolism.
- Mechanism: Regulates epidermal keratinocyte differentiation and keratin metabolism, unblocks blocked hair follicle sebaceous gland ducts, reduces follicular keratosis, inhibits mild inflammatory reaction of acne, and improves acne skin lesions.
- Drug class: Topical retinoid acne treatment agent.
- Clinical use: First-line external drug for clinical standardized treatment of mild to moderate acne vulgaris.
| Generic Name | Adapalene Gel |
| Brand Name | Differin®; MingKangXin® |
| Ingredient | Adapalene |
| Dosage Form | Gel |
| Package | Differin:
30g (0.1%) *1 tube/box MingKangXin: 15g: 15mg*10g*1 tube/box; 15g: 15mg*15g*1 tube/box; 15g: 15mg*30g*1 tube/box |
| Conditions Treated | Acne vulgaris, facial comedones, inflammatory papules and pustules |
| Taboos | Contraindicated in patients allergic to adapalene and gel excipients; prohibited for pregnant women and individuals with severe facial skin damage |
| Place of origin | Zone Industrielle Montdesir, Alby Sur Cheran, 74540, France; China |
| Prescription type | Prescription-only; OTC |
| Storage Conditions | Sealed storage in a cool and dark place, avoid high temperature and freezing environment |
| Manufacturer | Laboratoires Galderma; Sichuan Med-shine Pharmaceutical Co., Ltd. |
| Registration Authority | National Medical Products Administration (NMPA), China |
| Approval number | HJ20160022; H20065544 |
| Approval Date | Sept 3, 2025; Jul 28, 2025 |
| Shelf Life | 24 months |
How to use ?
Recommended Dose: Apply a thin layer of gel evenly to the acne lesion area once a day at night.
Time: Topical application once daily before bedtime.
Instructions for use: Clean and dry the facial skin before application, avoid contact with eye, lip and nasal mucous membranes.
Interaction: Avoid simultaneous use of other irritating anti-acne external preparations to prevent excessive skin irritation.
Side effects: Early medication may cause local skin dryness, peeling, redness and slight stinging, which can adapt gradually.
Important Notice
This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indicatiaon, and regional regulatory requirements.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What skin problems can original Adapalene Gel improve?
It treats acne vulgaris and improves skin conditions of comedones, inflammatory papules and pustules.
What is the correct application time of Adapalene Gel?
The gel should be applied evenly to the affected skin once a day before bedtime.
Which groups are prohibited from using Adapalene Gel this anti-acne gel?
Pregnant women, people allergic to the ingredients and those with severe facial skin damage cannot use it.
What skin reactions may occur in the early stage of medication of Adapalene Gel?
Early use may cause temporary skin dryness, peeling, redness and slight stinging sensation.
Differin® | Adapalene Gel | Acne/Pimples/Papules/Pustules | DengYueRX
INN: Adapalene Gel
Indications: Acne, pimples, papules, pustules
Dosage Form: Gel
Strength: 30g (0.1%) /tube; 15g: 15mg*10g/tube
Price range: $1.57 through $10.45
