alimta pemetrexed disodium for injection 500mg per vial

Description

Indication & Scope

Pemetrexed Disodium for Injection (Alimta®) is a multi-target folate metabolic inhibitor. It simultaneously inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase, blocks de novo synthesis of purines and pyrimidines, suppresses tumor cell proliferation and induces tumor cell death.

Mechanism
Multi-target folate metabolism inhibitor
Drug class
Prescription injectable cytotoxic anti-tumor drug
Clinical use
Malignant pleural mesothelioma, non-squamous non-small cell lung cancer

Specification

Generic Name	Pemetrexed Disodium for Injection
Brand Name	Alimta®
Ingredient	Pemetrexed Disodium
Dosage Form	Injection
Package	500mg/vial
Conditions Treated	First-line therapy for locally advanced/metastatic non-squamous NSCLC: combined with cisplatin, pembrolizumab or sintilimab plus platinum (EGFR/ALK wild-type); Second-line monotherapy for recurrent non-squamous NSCLC post prior chemotherapy
Taboos	Patients with severe hypersensitivity to pemetrexed or any excipients
Place of origin	Pallini Attiki, Greece
Priscription Type	Prescription Drug
Storage Conditions	Sealed, store below 25°C, protected from light
Manufacturer	Vianex S.A.-Plant C
Registration Authority	National Medical Products Administration (NMPA)
Approval number	HJ20140662
Approval Date	November 26, 2024
Shelf Life	36 months

How to use ?

Recommended Dose: Standard dosage regimen: 500 mg/m² intravenous infusion over 10 minutes on Day 1 of each 21-day cycle.

Time: 21 days as one treatment cycle, administered only on Day 1 of each cycle, with or without food restriction.

Interaction: NSAIDs increase pemetrexed exposure in renal impaired patients, close renal function monitoring required.

Side effects: Common reactions: Neutropenia, anemia, thrombocytopenia, fatigue, nausea, vomiting, stomatitis, rash, diarrhea, elevated transaminase.

Important Notice

This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support