Home - Prescription Medicines - Tagrisso® | Osimertinib Mesylate Tablets | NSCLC | DengYueRX
Description
Indication & Scope
Osimertinib Mesylate Tablets (Tagrisso®) is an irreversible third‑generation EGFR‑TKI. It potently inhibits EGFR sensitizing mutations (19del, L858R) and resistance mutation T790M, blocking downstream signaling to suppress lung cancer growth. It spares wild‑type EGFR and causes fewer adverse reactions.
- Mechanism
Irreversibly inhibit mutant EGFR, block downstream tumor signaling, suppress tumor cell growth - Drug class
Third-generation irreversible EGFR-TKI oral targeted anti-tumor agent - Clinical use
EGFR-mutant non-small cell lung cancer (adjuvant, first-line, maintenance and second-line treatment)
| Generic Name | Osimertinib Mesylate Tablets |
| Brand Name | Tagrisso® |
| Ingredient | Osimertinib Mesylate |
| Dosage Form | Film-coated Tablets |
| Package | 80mg*30 tablets/box |
| Conditions Treated | NSCLC (Non-Small Cell Lung Cancer), EGFR (Epidermal Growth Factor Receptor) |
| Taboos | Hypersensitivity to osimertinib mesylate or any excipients, concomitant St John’s Wort administration, pregnancy |
| Place of origin | Gartunavagen, SE-152 57 Sodertalje, Sweden |
| Priscription Type | Prescription drug (Rx) |
| Storage Conditions | Store in original packaging, protected from light, no special temperature control required |
| Manufacturer | AstraZeneca AB |
| Registration Authority | National Medical Products Administration (NMPA) |
| Approval number | HJ20170167 |
| Approval Date | January 06, 2026 |
| Shelf Life | 36 months |
How to use ?
Recommended Dose: Standard dose: 80mg oral once daily;Dose adjustment: Increase to 160mg qd when combined with strong CYP3A4 inducers; reduce to 40mg qd or discontinue permanently for severe adverse reactions;Administration: Swallow whole tablet with water, with or without food, do not crush or split
Time: Continuous administration until disease progression or intolerable toxicity for advanced tumors; adjuvant treatment lasts for 3 years
Interaction: Avoid strong CYP3A4 inducers and QT-prolonging agents; monitor toxicity when combined with CYP3A4 inhibitors and BCRP substrates
Side effects: Diarrhea, rash, dry skin, nail disorders, stomatitis, fatigue, leukopenia, neutropenia, musculoskeletal pain; severe risks include interstitial lung disease, QT interval prolongation, decreased LVEF
Important Notice
This product shall only be used for post-exposure rabies prophylaxis by professional medical staff. It must be applied combined with rabies vaccine and injected via wound infiltration plus intramuscular routes as specified. Do not administer intravenously or alter the dosage at will. Hypersensitivity monitoring is required throughout the whole injection process.
Packaging & Shipping
Packaging
Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.
Shipping Methods
Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.
Export Support
Certificate of Analysis
GMP Certificate
Commercial Invoice
Packing List & CPP
Cold Chain Logistics
Customs Documentation
Scientific and regulatory sources
FAQ
What generation EGFR-TKI is osimertinib?
Irreversible third-generation EGFR tyrosine kinase inhibitor.
Can patients take osimertinib on an empty stomach?
Yes, taking with or without food is acceptable.
What examination must be completed before medication initiation?
Validated EGFR gene mutation testing.
Which EGFR mutation is the main target for second-line treatment?
EGFR T790M mutation.
Tagrisso® | Osimertinib Mesylate Tablets | NSCLC | DengYueRX
INN: Osimertinib Mesylate
Indications: NSCLC (Non-Small Cell Lung Cancer)
Dosage Form: Film-coated Tablets
Strength: 80mg/Tablet
$882.35 Original price was: $882.35.$750.00Current price is: $750.00.