Description

Indication & Scope

Tretinoin Cream is a topical preparation containing tretinoin, a derivative of vitamin A. It is indicated for the topical management of acne vulgaris and certain disorders associated with abnormal keratinization. The product should be used according to the approved labeling and medical or pharmacist guidance.

Mechanism:Tretinoin is a topical retinoid that regulates epidermal cell differentiation and proliferation. It helps normalize abnormal follicular keratinization and promotes the turnover of epidermal cells, thereby reducing the formation of comedones.
Drug class:Topical retinoid
Clinical use:Primarily used for topical management of acne vulgaris and certain keratinization disorders.

Specification

Generic Name	Tretinoin Cream
Brand Name	Hongke
Ingredient	Tretinoin 0.25 mg/g (0.025%)
Dosage Form	Cream
Package	18 g/tube, 1 tube/box
Conditions Treated	Acne vulgaris; keratinization disorders
Taboos	Contraindicated in patients allergic to vitamin A derivatives, pregnant women, and patients with acute or subacute dermatitis or eczema.
Place of origin	China
Prescription type	Non-prescription drug (OTC) according to available product listings.
Storage Conditions	Store tightly closed, protected from light and moisture, in a cool place.
Manufacturer	Hubei Kangzheng Pharmaceutical Co., Ltd.
Registration Authority	National Medical Products Administration (NMPA), China
Approval Number	H20055512
Approval Date	2010-06-30
Shelf Life	24 months

How to use ?

Recommended Dose: For acne vulgaris, apply an appropriate amount to the affected area once daily.

Time: Usually once nightly before bedtime.

Instructions for use: Clean and dry the affected area before application. Apply a thin layer of the cream to the affected skin. Avoid contact with the eyes, mouth, nose, mucous membranes and damaged skin. Avoid excessive application or application over large areas. Sun exposure to treated areas should be minimized.

Interaction: Concomitant use with other topical preparations that cause irritation, including certain acne treatments, may increase local skin irritation. Patients using other medicines should consult a doctor or pharmacist before combining treatments.

Side effects: Common local reactions may include erythema, swelling, dryness, peeling, crusting, burning or irritation. Changes in skin pigmentation may also occur. Tretinoin can temporarily make acne lesions appear more noticeable during the initial treatment period.

Important Notice

This product should be administered only by qualified healthcare professionals in accordance with the approved prescribing information and local clinical guidelines. Dosage and administration may vary depending on patient condition, indication, and regional regulatory requirements.

Packaging & Shipping

Packaging

Original manufacturer’s packaging with secure export carton. Customized export packaging is available upon request.

Shipping Methods

Express Courier (EMS, DHL, FedEx, UPS), Air Freight, and Sea Freight. Cold-chain transportation is available for products requiring temperature-controlled logistics.

Export Support

Certificate of Analysis

GMP Certificate

Commercial Invoice

Packing List & CPP

Cold Chain Logistics

Customs Documentation

Scientific and regulatory sources

1.WHO References

2.NMPA

3.FDA

4.EMA

FAQ

What is Tretinoin Cream used for?

Tretinoin Cream is a topical retinoid indicated for acne vulgaris and certain disorders involving abnormal keratinization.

How often should Tretinoin Cream be applied?

For acne vulgaris, the product is generally applied once daily at night before bedtime, following the approved instructions.

Can Tretinoin Cream be used during pregnancy?

The available product information lists pregnancy as a contraindication. Pregnant women should not use this product.

What skin reactions can occur during treatment?

Local irritation, redness, peeling, dryness, burning or changes in pigmentation may occur. If severe irritation develops, use should be discontinued and medical advice sought.